PHOSPHATIDYLETHANOLAMINE

PHOSPHATIDYLETHANOLAMINE Structure
CAS No.
39382-08-6
Chemical Name:
PHOSPHATIDYLETHANOLAMINE
Synonyms
Cephalins;L-A-PHOSPHATIDYLETHANOLAMINE TYPE III:*F ROM EGG YOL;1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin;1,2-Diacyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, L-α-Cephalin;Kephalins;E COLI PE;Cephalinex;PE/Cephalin;l-α-cephalin;Phospholipids cephalins
CBNumber:
CB7198531
Molecular Formula:
C41H78NO8P
Molecular Weight:
744.033681
MOL File:
39382-08-6.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:16

PHOSPHATIDYLETHANOLAMINE Properties

Density approximate 1.47g/ml(20℃)
storage temp. -20°C
solubility chloroform: 50 mg/mL, slightly hazy, brown-yellow
form solution
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H302-H315-H319-H331-H336-H351-H361d-H372-H412
Precautionary statements  P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
Hazard Codes  Xn
Risk Statements  22-38-40-48/20/22-67-36/38-20-63-68/20/21/22-20/21/22-20/22
Safety Statements  36/37-26
RIDADR  UN 1888 6.1/PG 3
WGK Germany  3
1-8-10
HS Code  2923202000

PHOSPHATIDYLETHANOLAMINE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P8193 L-α-Phosphatidylethanolamine from Glycine max (soybean) Type IV, ≥98% (TLC), lyophilized powder 39382-08-6 25MG ₹21325.25 2022-06-14 Buy
Sigma-Aldrich(India) P7943 L-α-Phosphatidylethanolamine from egg yolk Type III, ≥97% (TLC), lyophilized powder 39382-08-6 5MG ₹4427.43 2022-06-14 Buy
Sigma-Aldrich(India) P8193 L-α-Phosphatidylethanolamine from Glycine max (soybean) Type IV, ≥98% (TLC), lyophilized powder 39382-08-6 100MG ₹78784.35 2022-06-14 Buy
Sigma-Aldrich(India) P7943 L-α-Phosphatidylethanolamine from egg yolk Type III, ≥97% (TLC), lyophilized powder 39382-08-6 25MG ₹16811.23 2022-06-14 Buy
Sigma-Aldrich(India) P7943 L-α-Phosphatidylethanolamine from egg yolk Type III, ≥97% (TLC), lyophilized powder 39382-08-6 100MG ₹48560.95 2022-06-14 Buy
Product number Packaging Price Buy
P8193 25MG ₹21325.25 Buy
P7943 5MG ₹4427.43 Buy
P8193 100MG ₹78784.35 Buy
P7943 25MG ₹16811.23 Buy
P7943 100MG ₹48560.95 Buy

PHOSPHATIDYLETHANOLAMINE Chemical Properties,Uses,Production

Uses

L-α-Phosphatidylethanolamine from egg yolk has been used:

  • as a component of lipid mixture for the synthesis of giant unilamellar vesicles (GUVs)
  • in ceramide phosphoethanolamine (CPE) synthase assay using crude sphingomyelin synthase-related protein from Hela cells
  • for the standard curve generation for the quantification of lipids in plantaris muscle homogenates from mice

General Description

L-α-Phosphatidylethanolamine from egg yolk has high unsaturated fatty acid content and elicits radical-scavenging activity. L-α-Phosphatidylethanolamine (PE) is a membrane phospholipid and is interconverted to phosphotidylserine in the presence of phosphatidylserine synthase 2. PE is essential for maintaining the structural integrity of membranes. It is the second most abundant phospholipid in animals, plants and yeast and the major lipid in bacteria. It is synthesized in mitochondria in mammals.

Enzyme inhibitor

This hygroscopic phospholipid, also called cephalin and 1,2-diacyl-snglycero- 3-phosphoethanolamine, is an important constituent of biomembranes and lipoproteins. It is the major structural phospholipid in brain tissue. The physical properties depend on the nature of the acyl groups and on the presence of other lipids. Freshly prepared phosphatidylethanolamines are white solids that turn yellow and brown on exposure to air. They typically sinter between 80 and 90°C and melt in the neighborhood of 175°C. Solutions of phosphatidylethanolamine slowly decompose at room temperature (roughly 0.3-0.5% per day); hence, solutions should always be freshly prepared and kept cold prior to use. It is labile in alkaline conditions. See also specific compound Target(s): b- N-acetylglucosaminyl-glycopeptide b-1,4-galactosyltransferase; Nacetyllactosamine synthase; acylglycerol kinase, or monoacylglycerol kinase; cholesterol monooxygenase, side-chain-cleaving, or CYP11A1; chymase; cytidylate cyclase; dolichyldiphosphatase; dolichyl-phosphatase; dopamine b-monooxygenase; ethanolaminephosphotransferase; glutamate dehydrogenase; γ-glutamyl transpeptidase, mildly inhibited; glycerol-3-phosphate Oacyltransferase; glycerone-phosphate O-acyltransferase, or dihydroxyacetione-phosphate O-acyltransferase; hormone-sensitive lipase; 3-hydroxybutyrate dehydrogenase; indole-3-acetate b-glucosyltransferase; phosphatidate cytidylyltransferase; 1- phosphatidylinositol 4-kinase; phosphoinositide phospholipase C; phospholipase D, phosphatidylcholine-specific enzyme; sphingomyelin phosphodiesterase; steryl-b-glucosidase; UDP-Nacetylglucosamine: dolichyl-phosphate N-acetylglucosaminephosphotransferase.

Purification Methods

Purify the cephalin by dissolving it in EtOH, adding Pb(OAc)2.3H3O (30g in 100mL H2O) until excess Pb2+ is present. Filter off the solid. Pass CO2 gas through the solution until precipitation of PbCO3 ceases. Filter the solid off and evaporate (while bubbling CO2) under vacuum. An equal volume of H2O is added to the residual oil and extracted with hexane. The hexane extract is washed with H2O until the aqueous phase is free from Pb [test with dithizone (2 mg in 100 mL CCl4; Feigel Spot Tests Vol I, Elsevier p. 10 1954)]. The hexane is dried (Na2SO4), filtered and evaporated to give a yellow waxy solid which should be dried to constant weight in vacuo. It is practically insoluble in H2O and Me2CO, but freely soluble in CHCl3 (5%) and Et2O, and slightly soluble in EtOH. [Schofield & Dutton Biochemical Preparations 5 5 1957.]

PHOSPHATIDYLETHANOLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

PHOSPHATIDYLETHANOLAMINE Suppliers

Global( 84)Suppliers
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 25247 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Alfa Chemistry United States 24072 58 Inquiry
Nanjing Duly Biotech Co.,Ltd +undefined18013301590 China 2452 58 Inquiry
ZHEJIANG JIUZHOU CHEM CO., LTD +86-0576225566889 +86-13454675544 China 12272 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
[(2R)-1-[2-azanylethoxy(hydroxy)phosphoryl]oxy-3-pentadecanoyloxy-propan-2-yl] icosanoate arachidic acid [(1R)-1-[[2-aminoethoxy(hydroxy)phosphoryl]oxymethyl]-2-pentadecanoyloxy-ethyl] ester PHOSPHATIDYLCHOLINE(EGG)(RG) 3-sn-Phosphatidylethanolamine solution,L-α-Cephalin L-α-Phosphatidylethanolamine from egg yolk,1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin L-α-Phosphatidylethanolamine from Escherichia coli,1,2-Diacyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, L-α-Cephalin L-α-Phosphatidylethanolamine from Glycine max (soybean),1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin 3-SN-PHOSPHATIDYLETHANOLAMINE E COLI L-A-PHOSPHATIDYLETHANOLAMINE TYPE V-A L-A-PHOSPHATIDYLETHANOLAMINE TYPE V*FROM ESCHERICHI 3-SN-PHOSPHATIDYLETHANOLAMINE SOLUTION, FROM SOYBEAN 3-SN-PHOSPHATIDYLETHANOLAMINE FROM E. CO LI L-A-PHOSPHATIDYLETHANOLAMINE TYPE III L-A-PHOSPHATIDYLETHANOLAMINE TYPE IX*FRO M ESCHERICH L-A-PHOSPHATIDYLETHANOLAMINE TYPE IV:*FR OM SOYBEAN L-A-PHOSPHATIDYLETHANOLAMINE*TYPE VII-A FROM BOVINE L-A-PHOSPHATIDYLETHANOLAMINE TYPE VII:*F ROM BOVINE L-A-PHOSPHATIDYLETHANOLAMINE TYPE VII*FR OM BOVINE L 3-SN-PHOSPHATIDYLETHANOLAMINE SOLUTION, FROM EGG YOLK L-A-PHOSPHATIDYLETHANOLAMINE TYPE III*FR OM EGG YOLK PhosphatidylethanolamineExEgg l-α-cephalin l-α-phosphatidylethanolamine from egg yolk l-α-phosphatidylethanolamine from escherichia coli l-α-phosphatidylethanolamine from glycine max (soybean) L-ALPHA-PHOSPHATIDYLETHANOLAMINE SOLUTION, EGG YOLK L-LPHA-PHOSPHATIDYLETHANOLAMINE FRO L-A-PHOSPHATIDYLETHANOLAMINE TYPE IV 3-sn-phosphatidylethanolaminesolution PHOSPHATIDYLETHANOLAMINE Phosphatidylethanolamine (100 mg) (INTERNATIONAL COLD CHAIN SHIPMENT REQUIRED) Cephalinex Glycerophospholipids cephalins Kephalins Phospholipids cephalins L-3-PHOSPHATIDYLETHANOLAMINE L-ALPHA-CEPHALIN E COLI L-ALPHA-CEPHALIN TYPE V ESCHERICHIA COLI L-ALPHA-PHOSPHATIDYLETHANOLAMINE TYPE V ESCHERICHIA COLI L-A-PHOSPHATIDYLETHANOLAMINE (E COLI) E COLI PE 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE TYPE V ESCHERICHIA COLI Phosphatidylethanolamine (100 mg) (COLD SHIPMENT REQUIRED) L-alpha-Phosphatidylethanolamine from Glycine max (soybean) L-alpha-Phosphatidylethanolamine from egg yolk Phosphatidylethanolamine from soya bean PHOSPHATIDYLETHANOLAMINE (PE) (18R,21S)-24-Amino-21-hydroxy-21-oxido-15-oxo-16,20,22-trioxa-21λsup5sup-phosphatetracosan-18-ylicosanoate PHOSPHATIDYLETHANOLAMINE ISO 9001:2015 REACH L-α-Phosphatidyleth an olamine 1,2-Diacyl-sn-glycero-3-phosphoethanolamine, L-α-Cephalin 1,2-Diacyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, L-α-Cephalin Cephalins L-A-PHOSPHATIDYLETHANOLAMINE TYPE III:*F ROM EGG YOL Phosphatidylethanolamine (chicken egg) L-α-Phosphatidylethanolamine from egg yolk PE/Cephalin 39382-08-6