GMDP
![GMDP Structure](CAS/GIF/70280-03-4.gif)
- CAS No.
- 70280-03-4
- Chemical Name:
- GMDP
- Synonyms
- GMDP;syl)muramoyl)-l-alanyl-;glucosaminylmuramyldipeptide;4-(2-ACETAMIDO-2-DEOXY-B-D- &;4-(2-acetamido-2-deoxy-B-D-*glucopyranosyl)-N-ace;d-glcnac-β-(1→4)-n-acetylmuramyl-l-ala-d-isoglutamine;D-GLCNAC-BETA-(1->4)-N-ACETYLMURAMYL-L-ALA-D-ISOGLUTAMINE;N-Acetyl-D-glucosaminyl-(b1,4)-N-acetylmuramyl-L-alanyl-D-io;n-acetylglucosaminyl-n-acetylmuramyl-l-alanyl-d-isoglutamine;n-acetyl-beta-glucosaminyl-n-acetylmuramyl-alanylisoglutamine
- CBNumber:
- CB7201998
- Molecular Formula:
- C27H45N5O16
- Molecular Weight:
- 695.67
- MOL File:
- 70280-03-4.mol
- Modify Date:
- 2023/5/4 17:34:41
GMDP Chemical Properties,Uses,Production
Description
N-acetyl-β-D-glucosaminyl-( 1→4)-N-acetylmuramyl-L-alanyl-D-isoglutamine was launched in Russia for hospital-related infections, psoriasis, cervical precancerous lesions and ophthalmic keratitis caused by herpes. It was found to be less pyrogenic than MDP, the minimally active component of Freund's complete adjuvant. While chemical synthesis is possible, a less laborious method (3 steps) involves the enzymatic degradation of a bacterial peptidoglycan. GDMP is orally active with a low toxicity that acts as an adjuvant to highly purified protein antigens to stimulate the induction of CD8* T-cell response. It was also able to reduce the levels of TNF-α, IL-1α and hypoglycemia induced by LPS administration and to inhibit systemic response to endotoxin.
Originator
Peptech (Australia)
brand name
Likopid
GMDP Preparation Products And Raw materials
Raw materials
Preparation Products
GMDP Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
EMD Biosciences, Inc. | 858 450 5500 | United States | 6529 | 66 | Inquiry |
VWR International | 800 932 5000 | United Kingdom | 6554 | 82 | Inquiry |
MP Biomedicals, Inc. | 949 833 2500 | United States | 6566 | 81 | Inquiry |
SIGMA-RBI | 800 736 3690 (Orders) | Switzerland | 6913 | 91 | Inquiry |
Riedel-de Haen AG | 800 558-9160 | United States | 6825 | 87 | Inquiry |
Nanjing Peptide Biotech Ltd. | 025-025-58361106-805-805 13082558573 | China | 9978 | 55 | Inquiry |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | China | 18021 | 56 | Inquiry |
Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | China | 30968 | 58 | Inquiry |
Supplier | Advantage |
---|---|
EMD Biosciences, Inc. | 66 |
VWR International | 82 |
MP Biomedicals, Inc. | 81 |
SIGMA-RBI | 91 |
Riedel-de Haen AG | 87 |
Nanjing Peptide Biotech Ltd. | 55 |
ChemStrong Scientific Co.,Ltd | 56 |
Nantong Hanfang Biotechnology Co. , Ltd. | 58 |
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