(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol

(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol Structure
CAS No.
1006376-60-8
Chemical Name:
(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
Synonyms
(ALPHAS)-ALPHA;Tigrelo Impurity 45;(1S)-2-Chloro-1-(3,4-difluorophenyl)ethan-1-ol;(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol;Benzenemethanol, α-(chloromethyl)-3,4-difluoro-;Benzenemethanol, α-(chloromethyl)-3,4-difluoro-, (αS)-;(alphaS)-alpha-(Chloromethyl)-3,4-difluorobenzenemethanol
CBNumber:
CB72603392
Molecular Formula:
C8H7ClF2O
Molecular Weight:
192.59
MOL File:
1006376-60-8.mol
Modify Date:
2023/5/15 10:43:23

(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol Properties

Boiling point 256.3±35.0 °C(Predicted)
Density 1.372±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form viscous liquid
pka 12.49±0.20(Predicted)
color Clear, almost colourless

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H315-H317-H319-H334-H335
Precautionary statements  P261-P280-P301+P310-P305+P351+P338-P342+P311
HS Code  2906290090

(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol Chemical Properties,Uses,Production

Uses

(S)-2-Chloro-1-(3,4-difluorophenyl)ethanol is a building block used in organic synthesis including bein an intermediate in the synthesis of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.

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(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol Spectrum

(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol (1S)-2-Chloro-1-(3,4-difluorophenyl)ethan-1-ol (alphaS)-alpha-(Chloromethyl)-3,4-difluorobenzenemethanol Benzenemethanol, α-(chloromethyl)-3,4-difluoro-, (αS)- Benzenemethanol, α-(chloromethyl)-3,4-difluoro- (ALPHAS)-ALPHA Tigrelo Impurity 45 1006376-60-8