14β-Hydroxydeacetylbaccatin III

14β-Hydroxydeacetylbaccatin III Structure
CAS No.
145533-34-2
Chemical Name:
14β-Hydroxydeacetylbaccatin III
Synonyms
4β-Hydroxy-10-DAB;Docetaxel Impurity 17;Docetaxel Impurity 59;14-Hydroxy-10-deacetylbaccatin;14β-Hydroxydeacetylbaccatin III;10-Deacetyl-14β-hydroxybaccatin III;14β-Hydroxy-10-deacetylbaccatin III;14β-Hydroxy-10-desacetylbaccatin III;14β-Hydroxy 10-Deacetyl Baccatin III;13-epi-14Beta-Hydroxy-10-deacetyl Baccatin III
CBNumber:
CB72622199
Molecular Formula:
C29H36O11
Molecular Weight:
560.59
MOL File:
145533-34-2.mol
Modify Date:
2023/4/23 13:52:06

14β-Hydroxydeacetylbaccatin III Properties

Melting point 218-220°C (dec.)
Boiling point 717.6±60.0 °C(Predicted)
Density 1.46±0.1 g/cm3(Predicted)
solubility DMSO, Methanol
pka 11.33±0.70(Predicted)
form Solid
color Off-White

14β-Hydroxydeacetylbaccatin III Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

14β-Hydroxy 10-Deacetyl Baccatin III is a novel derivative of 10-Deacetylbaccatin III (D198250) with antitumor and antimitotic activity.

14β-Hydroxydeacetylbaccatin III Preparation Products And Raw materials

Raw materials

Preparation Products

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(2aR,4S,4aS,6R,9R,10S,11R,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,10,11-pentahydroxy-4a,8,13,13-tetraMethyl-7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one 10-Deacetyl-14β-hydroxybaccatin III 14β-Hydroxy 10-Deacetyl Baccatin III 14β-Hydroxy-10-deacetylbaccatin III 14β-Hydroxy-10-desacetylbaccatin III 4β-Hydroxy-10-DAB 14β-Hydroxy 10-Deacetyl Baccatin III DISCONTINUED Paclitaxel impurity 5/10-Deacetyl-14-Hydroxy-Baccatin III/[(1R,2S,3R,4S,7R,9S,10S,12R,15R,16S)-4-acetyloxy-1,9,12,15,16-pentahydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate Docetaxel Impurity 17 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,10,11-pentahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9R,10S,11R,12S,12aR,12bS)- 14-Hydroxy-10-deacetylbaccatin Docetaxel Impurity 59 13-epi-14Beta-Hydroxy-10-deacetyl Baccatin III 14β-Hydroxydeacetylbaccatin III 145533-34-2 Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals