Valsartan D9
- CAS No.
- 1089736-73-1
- Chemical Name:
- Valsartan D9
- Synonyms
- [2H9]-Valsartan;rac-Valsartan D9;2H9]-Valsartan(major);Cefuroxime Impurity 73;[2H9]-Valsartan (mixture);ACWBQPMHZXGDFX-KDDXQTGLSA-N;VALSARTAN-D9 (D7-D9 MIXTURE);L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-;(2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid;Valsartan D9Q: What is Valsartan D9 Q: What is the CAS Number of Valsartan D9 Q: What is the storage condition of Valsartan D9 Q: What are the applications of Valsartan D9
- CBNumber:
- CB72640030
- Molecular Formula:
- C24H29N5O3
- Molecular Weight:
- 435.53
- MOL File:
- 1089736-73-1.mol
- Modify Date:
- 2024/7/2 8:55:16
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361-H402-H412 |
| Precautionary statements | P201-P202-P273-P280-P308+P313-P405-P501 |
Valsartan D9 Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
Biological Activity
Valsartan-d9 is intended for use as an internal standard for the quantification of valsartan by GC- or LC-MS. Valsartan is a nonpeptide antagonist of the angiotensin II type 1 (AT1) receptor (IC50 = 2.7 nM). It is 20,000-fold selective for AT1 over AT2 and, unlike some other AT receptor antagonists, does not alter peroxisome proliferator-activated receptor γ (PPARγ) activity in vitro. In vivo, valsartan (30 mg/kg) increases cardiac output and reduces left ventricular fibrosis in a model of heart failure with reduced ejection fraction in mice with streptozotocin-induced diabetes. Formulations containing valsartan have been used in the treatment of hypertension and heart failure.
Valsartan D9 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SIMSON PHARMA LIMITED | +91-8291074273 | Shanghai, India | 228 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | China | 30968 | 58 | Inquiry |
| Cato Research Chemicals Inc. | 020-81960175-877 18933936954 | China | 7730 | 58 | Inquiry |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | China | 12582 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 15002134094 | China | 28091 | 58 | Inquiry |
| SHANGHAI ZZBIO CO., LTD. | 13916577892 19921389125 | China | 12063 | 58 | Inquiry |
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