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Micafungin FR-179642 impurity (acid)

Micafungin FR-179642 impurity (acid) Structure
CAS No.
168110-44-9
Chemical Name:
Micafungin FR-179642 impurity (acid)
Synonyms
FR-179642;Micafungin FR-179642;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0;FRAN;MFA/CBR03-2;FR179642, CMICA;FR 179642 (~90%);Micafungin Nucleus;US-DMF No.: 030028;N-1 Micafungin Sodium
CBNumber:
CB72657658
Molecular Formula:
C35H52N8O20S
Molecular Weight:
936.89
MOL File:
168110-44-9.mol
MSDS File:
SDS
Modify Date:
2024/7/19 18:29:52

Micafungin FR-179642 impurity (acid) Properties

Melting point >150oC (dec.)
Density 1.75±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated)
pka -4.46±0.18(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H335-H412-H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P273-P501

Micafungin FR-179642 impurity (acid) Chemical Properties,Uses,Production

Uses

FR 179642 is an impurity of Micafungin (M342350), a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species.

Definition

Micafungin FR-179642 impurity (acid) is an impurity in micafungin that can be present as trace amounts in the final product and may contribute to hemolytic activity. This impurity is formed by hydrolysis during the synthesis process. Micafungin is an antifungal drug that inhibits the synthesis of ergosterol, a vital component of fungal cell membranes.

Micafungin FR-179642 impurity (acid) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 173)Suppliers
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
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Micafungin FR-179642 impurity (acid) Micafungin FR-179642 IMpurity N-1 Micafungin Sodium Micafungin Nucleus Micafungin Impurity FR-179642 Micafungin Sodium N-1 intermediate Micafungin Impurity 10 FR179642, CMICA MFA/CBR03-2 Pneumocandin A0, 1-[(4R,5R)-4,5-dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]- FR 179642 (~90%) FRAN US-DMF No.: 030028 TIANFU CHEM Micafungin FR-179642 impurity (acid) 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0 Micafungin FR-179642 FR-179642 Micafungin intermediates 168110-44-9 C35H52N8O20S