(S)-(-)-WARFARIN
- CAS No.
- 5543-57-7
- Chemical Name:
- (S)-(-)-WARFARIN
- Synonyms
- Warfarin,R-;(S)-WARFARIN;(S)-(-)-WARFARIN;Warfarin S-Isomer;Warfarin Impurity 17;Warfarin Impurity 17（Warfarin S-Isomer）;s-(-)-3-acetonybenzyl)-4-hydroxycoumarin;S-(-)-3-(ACETONYLBENZYL)-4-HYDROXYCOUMARIN;Warfarin sodium Impurity 23 ((S)-Warfarin);2-hydroxy-3-(3-keto-1-phenyl-butyl)chromone
- CBNumber:
- CB7267099
- Molecular Formula:
- C19H16O4
- Molecular Weight:
- 308.33
- MOL File:
- 5543-57-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:02:11
| Melting point | ≥170 °C |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 5 mg/ml |
| form | A crystalline solid |
| color | white to pale yellow |
| CAS DataBase Reference | 5543-57-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300+H310+H330-H360D-H372-H411 | |||||||||
| Precautionary statements | P202-P264-P273-P280-P302+P352+P310-P304+P340+P310 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 61-48/25-52/53 | |||||||||
| Safety Statements | 53-45-61 | |||||||||
| RIDADR | UN 2811 6.1/PG 1 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
(S)-(-)-WARFARIN price More Price(2)
(S)-(-)-WARFARIN Chemical Properties,Uses,Production
Description
(–)-Warfarin is a component of (±)-warfarin . It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. In vivo, (–)-warfarin slows formation of the prothrombin complex and exhibits 6.6-fold more potent anticoagulant activity than (+)-warfarin in rats. (–)-Warfarin is primarily metabolized by the cytochrome P450 (CYP) isoform CYP2C9 and genetic polymorphisms in this enyzme, as well as other compounds metabolized by CYP2C9, increase the potential for catastrophic bleeding complications. Formulations containing warfarin have been used to treat and prevent blood clots in atrial fibrillation, heart valve replacement, venous thrombosis, and pulmonary embolism.
Chemical Properties
White Solid
Uses
The S-(-)-form of Warfarin (W498500). Coumarin anticoagulant.
General Description
Warfarin is an antagonist of vitamin K. It is an oral coumarin anticoagulant.
(S)-(-)-WARFARIN Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 70)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Hebei Duling International Trade Co. LTD | +8617333973358 | China | 15438 | 58 | Inquiry |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | China | 11927 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
5543-57-7((S)-(-)-WARFARIN)Related Search:
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Coumarin, 3-(a-acetonylbenzyl)-4-hydroxy-, (S)-(-)- (8CI)
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-chromen-2-one
S-(-)-3-Acetonybenzyl)-4-hydroxycoumarin, S-(-)-4-Hydroxy-3-(3-oxo-1-phenybutyl)-2H-1-benzopyran-2-one
(-)-3-[(S)-1-Phenyl-3-oxobutyl]-4-hydroxycoumarin
(-)-3-[(S)-α-Acetonylbenzyl]-4-hydroxycoumarin
(-)-4-Hydroxy-3-[(S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one
2-hydroxy-3-(3-keto-1-phenyl-butyl)chromone
4-Hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one
(S)-(-)-WARFARIN
(S)-WARFARIN
(S)-(+)-4-HYDROXY-3-(3-OXO-1-PHENYBUTYL)-2H-1-BENZOPYRAN-2-ONE
S-(-)-4-HYDROXY-3-(3-OXO-1-PHENYBUTYL)-2H-1-BENZOPYRAN-2-ONE
(S)-(+)-4-HYDROXY-3-(3-OXO-1-PHENYLBUTYL)-2H-1-BENZOPYRAN-2-ONE
S-(-)-3-(ACETONYLBENZYL)-4-HYDROXYCOUMARIN
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
Warfarin,R-
(S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-HYDROXY-3-((S)-3-OXO-1-PHENYL-BUTYL)-CHROMEN-2-ONE
s-(-)-3-acetonybenzyl)-4-hydroxycoumarin
2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, (S)-
2H-1-Benzopyran-2-one, 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]- (9CI)
2-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-4-one
Warfarin S-Isomer
Warfarin Impurity 17（Warfarin S-Isomer）
Warfarin Impurity 17
S-(-)-WarfarinQ: What is
S-(-)-Warfarin Q: What is the CAS Number of
S-(-)-Warfarin Q: What is the storage condition of
S-(-)-Warfarin Q: What are the applications of
S-(-)-Warfarin
Warfarin sodium Impurity 23 ((S)-Warfarin)
5543-57-7
C19H16O4
Intermediates & Fine Chemicals
Pharmaceuticals
Aromatics
Chiral Reagents
Heterocycles