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Chlorpheniramine

Chlorpheniramine Structure
CAS No.
78539-96-5
Chemical Name:
Chlorpheniramine
Synonyms
CHLORPHENIRAMINE;dl-Chlorpheniramine;Dexchlorpheniramine Impurity 8
CBNumber:
CB7268733
Molecular Formula:
C16H19ClN2
Molecular Weight:
274.79
MOL File:
Mol file

Chlorpheniramine Properties

pka pKa 9.16±0.02(H2O t = 25 c = 0.002 to 0.01) (Uncertain)

Chlorpheniramine Chemical Properties,Uses,Production

Description

Chlorpheniramine is an antihistamine. Antihistamines are medications used to relieve symptoms of allergies, hay fever (allergic rhinitis), and the common cold. These symptoms include sneezing, runny nose, watery eyes, and itchy throat. Chlorpheniramine is sold under different brand names, including Chlor-Trimeton®.

Uses

Chlorpheniramine reduces the allergic response of the organism caused by histamine. It is used for allergy symptoms, rhinitis, and also as an ingredient in numerous compositions with ephedrine and pseudoephedrine, which are recommended for colds, upper respiratory tract infections, and allergic rhinitis. Synonyms of this drug are chlortrimeton, histaspan, tripolon, and teldrin.

Definition

Chlorphenamine is a tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma. It has a role as a H1-receptor antagonist, an antipruritic drug, a histamine antagonist, a serotonin uptake inhibitor, an antidepressant and an anti-allergic agent. It is a tertiary amino compound, a member of monochlorobenzenes and a member of pyridines.

Side effects

Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
confused, agitated, nervous
fast, irregular heartbeat
feeling faint, dizzy
seizures
tremor
trouble passing urine or change in the amount of urine
unusual sweating
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation or diarrhea
drowsy
dry mouth, nose, throat
headache
loss of appetite
stomach upset, vomiting
trouble sleeping

Chlorpheniramine Preparation Products And Raw materials

Raw materials

Preparation Products

Chlorpheniramine Suppliers

Global( 6)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Alltech Associates, Inc. 847 948 8600 United States 422 60 Inquiry
kemikalieimport + 45 - 2034 3359 Europe 6699 47 Inquiry
Guangzhou Dreampharm Biotechnology Co., Ltd. 020-36607679 17825480238 China 9843 12 Inquiry
Scinova Biotech(Guangzhou) Co., Ltd. 13268215580 China 7026 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd 029-81124267 15229202216 China 10011 58 Inquiry

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dl-Chlorpheniramine CHLORPHENIRAMINE Dexchlorpheniramine Impurity 8 78539-96-5