Pyridoxine hydrochloride
- CAS No.
- 58-56-0
- Chemical Name:
- Pyridoxine hydrochloride
- Synonyms
- Pyridoxine hydrochloride (Vitamin B6);campoviton6;5-Hydroxy-6-methyl-3,4-pyridinedimethanol;pyridox;paxadon;becilan;benadon;hexobion;hexermin;aderoxin
- CBNumber:
- CB8853882
- Molecular Formula:
- C8H12ClNO3
- Molecular Weight:
- 205.64
- MOL File:
- 58-56-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/3 15:34:43
| Melting point | 214-215 °C(lit.) |
|---|---|
| Density | 1.2784 (rough estimate) |
| vapor density | 7.1 (vs air) |
| refractive index | 1.5800 (estimate) |
| Flash point | 9℃ |
| storage temp. | room temp |
| solubility | H2O: 0.1 g/mL at 20 °C, clear, colorless |
| form | Crystalline Powder |
| color | White to almost white |
| PH Range | 3.2 |
| Water Solubility | 0.1 g/mL (20 ºC) |
| Sensitive | Light Sensitive |
| Merck | 14,7982 |
| BRN | 3632435 |
| BCS Class | 1 |
| Stability | Stable. Protect from air and light. |
| LogP | -1.098 (est) |
| CAS DataBase Reference | 58-56-0(CAS DataBase Reference) |
| EPA Substance Registry System | 5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride (58-56-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,T,F | |||||||||
| Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 26-37/39-45-36/37-16-7-24/25 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | UV1350000 | |||||||||
| F | 8-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29362500 | |||||||||
| NFPA 704 |
|
Pyridoxine hydrochloride price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P9755 | Pyridoxine hydrochloride ≥98% (HPLC) | 58-56-0 | 25G | ₹2749.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1036 | Pyridoxine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 58-56-0 | 500MG | ₹8356.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P9755 | Pyridoxine hydrochloride ≥98% (HPLC) | 58-56-0 | 100G | ₹8281.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P6280 | Pyridoxine hydrochloride BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture | 58-56-0 | 10G | ₹3972.78 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P6280 | Pyridoxine hydrochloride BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture | 58-56-0 | 25G | ₹5011.98 | 2022-06-14 | Buy |
Pyridoxine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Uses
Pyridoxine Hydrochloride is an acid form of vitamin b6, a water- soluble vitamin. it is soluble in water, and slightly soluble in alco- hol. it is slowly affected by sunlight and is reasonably stable in air. it has a ph of 2.3–3.5. it is also termed vitamin b6 hydrochloride. see pyridoxine.
Definition
ChEBI: Pyridoxine hydrochloride is the hydrochloride salt of pyridoxine. It is a hydrochloride and a vitamin B6. It contains a pyridoxine.
Application
Pyridoxine hydrochloride has been used:
As a vitamin component in a chemically defined diet with balanced metal content for metal depletion studies;
As a component of chemically defined medium (CDM) to culture Staphylococcus aureus WSPPA;
As analytical reference standards for the determination of analytes in pharmaceutical preparations by chromatography and spectrophotometric techniques;
As a vitamin to study the impact of protein expression and post-translational modifications specifically charge heterogeneity;
As a medicine, it is used to prevent or treat certain neurological disorders (peripheral neuropathy) caused by certain drugs (e.g. isoniazid). It is also used in the treatment of certain hereditary disorders (e.g. flavoururic aciduria, hyperoxaluria, homocystinuria).
General Description
Vitamin B6 has six forms namely, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Pyridoxine is a is a water-soluble vitamin and a pyrimidine derivative of vitamin B6. It is considered heat and acid stable.
Side effects
Common side effects of Pyridoxine hydrochloride include: headache, nausea, drowsiness, mild numbness or tingling. Serious allergic reactions are rare and include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing, decreased sensation of touch, temperature, and vibration; loss of balance or coordination. If serious side effects occur please seek medical attention.
Safety Profile
Poison by intravenous route. Moderately toxic by ingestion, intramuscular, and subcutaneous routes. Human reproductive effects by ingestion and intramuscular routes: postpartum changes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Purification Methods
Purify the vitamin by recrystallisation from EtOH/Me2CO, n-BuOH or MeOH/Et2O. Its solubility in H2O is 22%, and in EtOH it is 1.1%. It is insoluble in Et2O and CHCl3. Acidic aqueous solutions are stable at 120o/30minute. The free base has m 159-160o after recrystallisation from Me2CO and sublimation at 140-145o/0.0001mm. It has UV max at 290nm ( 84,000), 253 and 325nm ( 3,700 and 7,100) in 0.1N aqueous HCl. [Khua & Wendt Chem Ber 71 780 1938, 72 311 1939, Harris & Folkers J Am Chem Soc 61 1242 1939, Harris et al. J Am Chem Soc 62 3198 1940, Beilstein 21/5 V 492.]
Pyridoxine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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| Vardhaman P Golechha | 9704422000 | Telangana, India | 294 | 58 | Inquiry |
| Meteoric Biopharmaceuticals Pvt. Ltd. | +91-8511121361 +91-8511121361 | Mumbai, India | 71 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Suvan LifeSciences (formerly Sansh Biotech Pvt Ltd) | +91-1142631798 +91-9899000024 | New Delhi, India | 55 | 58 | Inquiry |
| Sonia Organics | 09845357114 | Karnataka, India | 13 | 58 | Inquiry |
| Bazayan & Co. | 91-22-28607070 | Maharashtra, India | 150 | 58 | Inquiry |
| Hexon Laboratories Pvt., Ltd. | 91-9767042000 | Maharashtra, India | 85 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
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