ChemicalBook > Product Catalog >API >Antipyretic analgesics >Antigout Drugs >D-Glucosamine hydrochloride
D-Glucosamine hydrochloride
- CAS No.
- 66-84-2
- Chemical Name:
- D-Glucosamine hydrochloride
- Synonyms
- GLUCOSAMINE HYDROCHLORIDE;GLUCOSAMINE HCL;D-GLUCOSAMINE HCL;D-Glucosamine Salt;Glucosamine for system suitability CRS;2-amino-2-deoxy-D-glucose hydrochloride (1:1);cosamin;NSC 758;D-GLCN HCL;NSC 234443
- CBNumber:
- CB2181059
- Molecular Formula:
- C6H14ClNO5
- Molecular Weight:
- 215.63
- MOL File:
- 66-84-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/11 18:14:38
| Melting point | 190-194 °C (dec.)(lit.) |
|---|---|
| alpha | 72.5 º (c=2, H2O, 5hrs.) |
| refractive index | 72 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear, colorless |
| form | crystalline |
| color | White |
| Water Solubility | soluble |
| Merck | 14,4458 |
| BRN | 4157370 |
| Stability | Stable. Incompatible with strong oxidizing agents. Combustible. |
| InChI | InChI=1/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/s3 |
| InChIKey | QKPLRMLTKYXDST-LPRXMDNASA-N |
| SMILES | [C@H]1(CO)OC([C@H](N)[C@@H](O)[C@@H]1O)O.Cl |&1:0,5,7,9,r| |
| LogP | -2.375 (est) |
| CAS DataBase Reference | 66-84-2(CAS DataBase Reference) |
| EPA Substance Registry System | D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | F,Xi,Xn | |||||||||
| Risk Statements | 21-36/38-46-62-63 | |||||||||
| Safety Statements | 24/25-53-36/37-26-25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | LZ6665000 | |||||||||
| F | 3-10 | |||||||||
| Hazard Note | Highly Flammable | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29329985 | |||||||||
| NFPA 704 |
|
D-Glucosamine hydrochloride price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G4875 | D-(+)-Glucosamine hydrochloride ≥99%, crystalline | 66-84-2 | 10MG | ₹2782.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G4875 | D-(+)-Glucosamine hydrochloride ≥99%, crystalline | 66-84-2 | 25G | ₹4330 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G4875 | D-(+)-Glucosamine hydrochloride ≥99%, crystalline | 66-84-2 | 100G | ₹12990 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1199 | Glucosamine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 66-84-2 | 500MG | ₹8508.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G4875 | D-(+)-Glucosamine hydrochloride ≥99%, crystalline | 66-84-2 | 500G | ₹29844.53 | 2022-06-14 | Buy |
D-Glucosamine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
white powder
Uses
Novel application of D-Glucosamine hydrochloride to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties.
General Description
Glucosamine, an amino sugar is generated form glucose and glutamine and is naturally produced in the body. Glucosamine, a endogenous amino monosaccharide is the major source of glucosamine-6-phosphate and n-acetylglucosamine.
Purification Methods
Crystallise the hydrochloride from 3M HCl, water, and finally water/EtOH/acetone as for galactosamine hydrochloride. [Purchase & Braun Org Synth 26 36 1946, Stacey & Webber Methods in Carbohydrate Chemistry I 228 1962, Academic Press.] The salt has also been purified by dissolving in the minimum volume of boiling H2O (charcoal), filtering and adding a large excess of 95% EtOH (~4 volumes) and stirring vigorously for several hours. Collect the crystals after 4-6hours to give anomer which mutarotates ] D +100o to +72o (equilibrium, c 1, H2O). A large amount of the -anomer stays in solution. This can be precipitated from the filtrate by adding excess Et2O. The mixture of -plus -anomers has [] D +68.8o (c 4.75, H2O, mutarotating to +70.1o)[Leaback Biochemical Preparations 10 118 1963]. Note that if Et2NH is used instead of Et3N, conversion to the -anomer can be complete (see above). [Stacey et al. Methods in Carbohydrate Chemistry I 3061962, Academic Press; Beilstein 4 IV 2018.]
D-Glucosamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 871)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Sonia Organics | +91-9538454135 +91-9538454135 | Karnataka, India | 28 | 58 | Inquiry |
| Meck Pharmaceuticals and Chemicals Pvt. Ltd. | +91-9898053709 +91-9898540709 | Gujarat, India | 44 | 58 | Inquiry |
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| R N Laboratories Pvt Ltd | 26472226736677 | Maharashtra, India | 10 | 58 | Inquiry |
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| Wanbury Limited | +91-2271963222 +91-2267942222 | Maharashtra, India | 17 | 58 | Inquiry |
| Prakruti Products Pvt Ltd | 09483929480 | Karnataka, India | 6 | 58 | Inquiry |
| Perennial Lifesciences Private Limited | 09810226012 | Delhi, India | 7 | 58 | Inquiry |
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