L-Alanine
- CAS No.
- 56-41-7
- Chemical Name:
- L-Alanine
- Synonyms
- ALANINE;L-ALA;H-ALA-OH;(S)-2-Aminopropanoic acid;2-Aminopropanoic acid;Alanin;H-L-ALA-OH;L-Ala-OH;L-alamine;L Alanine Powder
- CBNumber:
- CB4350297
- Molecular Formula:
- C3H7NO2
- Molecular Weight:
- 89.09
- MOL File:
- 56-41-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/15 20:03:10
| Melting point | 314.5 °C |
|---|---|
| alpha | 14.5 º (c=10,6N HCl,dry sub.) |
| Boiling point | 212.9±23.0 °C(Predicted) |
| Density | 1,432 g/cm3 |
| refractive index | 1.4650 (estimate) |
| FEMA | 3818 | DL-ALANINE |
| storage temp. | 2-8°C |
| solubility | H2O: 100 mg/mL |
| form | powder |
| pka | 2.34(at 25℃) |
| color | White to almost white |
| PH | 5.5-6.5 (100g/l, H2O, 20℃) |
| Odor | odorless |
| Odor Type | odorless |
| optical activity | [α]20/D +14.0±1°, c = 5% in 5 M HCl |
| Water Solubility | 166.5 g/L (25 ºC) |
| λmax |
λ: 260 nm Amax: ≤0.03 λ: 280 nm Amax: ≤0.02 |
| Merck | 14,204 |
| BRN | 1720248 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | QNAYBMKLOCPYGJ-REOHCLBHSA-N |
| LogP | -0.68 |
| CAS DataBase Reference | 56-41-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Alanine(56-41-7) |
| EPA Substance Registry System | L-Alanine (56-41-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AY2990000 | |||||||||
| F | 10 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29224995 | |||||||||
| NFPA 704 |
|
L-Alanine price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | W381829 | L-Alanine ≥99% | 56-41-7 | 1SAMPLE | ₹4968.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W381829 | L-Alanine ≥99% | 56-41-7 | 100G | ₹6852.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W381829 | L-Alanine ≥99% | 56-41-7 | 1KG | ₹16583.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A7627 | L-Alanine ≥98% (TLC) | 56-41-7 | 1G | ₹1860 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A7627 | L-Alanine ≥98% (TLC) | 56-41-7 | 100G | ₹5540 | 2022-06-14 | Buy |
L-Alanine Chemical Properties,Uses,Production
Description
L-Alanine is a non-essential amino acid. It is produced by direct β-decarboxylation of L-aspartate by L-aspartate β-decarboxylase or transamination of pyruvate in the glucose-alanine cycle and is a precursor for gluconeogenesis. Dysregulation of L-alanine metabolism is associated with various disease states, including diabetes, metabolic syndrome, ketotic hypoglycemia, and acquired acute lactic acidosis.
Chemical Properties
White crystalline powder
Physical properties
pI 6.01, dissociation constants: pK1 2.34, pK2 9.69.
Occurrence
Natural constituent of protein in plants and animals; found in apple, beef, carob, pea, soybean, wine and zucchini
Uses
L-Alanine plays a vital role in glucose-alanine cycle between tissue and liver. It is used for protein construction as well as involved in the metabolism of tryptophan and vitamin pyridoxine. It provides energy for muscles and central nervous system in order to strengthen the immune system. It helps in the metabolism of sugars and organic acids, and enhances the germination rates of Bacillus subtilis spores. It also displays a cholesterol-reducing effect in animals.
Preparation
Anthrobacter oxydans HAP-1 hyper produces DL-alanine in a nongrowth-associated manner.
Definition
ChEBI: The L-enantiomer of alanine.
Production Methods
L -Alanine is industrially produced from L -aspartic acid by means of immobilized Pseudomonas dacunhae cells in a pressurized bioreactor. An alanine racemase-deficient mutant of Arthro-bacter oxydans was reported, that produces75 g/L L -alanine from glucose with a yield of 52% and 95% e.e. A small amount of L -alanine is still isolated from protein hydrolysates.
General Description
L-Alanine, a non-essential amino acid,?is produced enzymatically from?L-aspartate using aspartate β-decarboxylase.?It is the smallest among all the amino acids.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Safety Profile
Mutation data reported. When heated to decomposition it emits toxic fumes of Nox
Purification Methods
Crystallise alanine from H2O or aqueous EtOH, i.e. crystallise it from 25% EtOH in water, or recrystallise it from 62.5% EtOH, wash it with EtOH and dry it to constant weight in vacuo over P2O5. [Gutter & Kegeles J Am Chem Soc 75 3893 1953, Walsh J Biol Chem 264 2394 1989.] 2,2'-Iminodipropionic acid is a likely impurity. [Beilstein 4 IV 2480. 2481.]
L-Alanine Preparation Products And Raw materials
Raw materials
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