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4-O-DesMethyl 4-O-Ethyl TriMethopriM

4-O-DesMethyl 4-O-Ethyl TriMethopriM Structure
CAS No.
78025-68-0
Chemical Name:
4-O-DesMethyl 4-O-Ethyl TriMethopriM
Synonyms
Methoxybenzyl impurity G;Methoxybenzene impurity G;Trimethoprim EP Impurity G;5-(4-Ethoxy-3,5-dimethoxybenzyl)pyr;Trimethoprim Impurity 7 (Trimethoprim EP Impurity G);5-(4-ethoxy-3,5-dimethoxybenzyl)pyrimidine-2,4-diamine;5-[(4-ethoxy-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine;2,4-Pyrimidinediamine, 5-[(4-ethoxy-3,5-dimethoxyphenyl)methyl]-;5-(4-Ethoxy-3,5-dimethoxybenzyl)pyrimidine-2,4-diamine (Trimethoprim Impurity)
CBNumber:
CB72709131
Molecular Formula:
C15H20N4O3
Molecular Weight:
304.34
MOL File:
78025-68-0.mol
Modify Date:
2023/4/23 13:52:06

4-O-DesMethyl 4-O-Ethyl TriMethopriM Properties

Melting point >170°C (dec.)
Boiling point 532.5±60.0 °C(Predicted)
Density 1.225±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form Solid
pka 7.05±0.10(Predicted)
color White to Beige

4-O-DesMethyl 4-O-Ethyl TriMethopriM Chemical Properties,Uses,Production

Uses

4-O-Desmethyl 4-O-Ethyl Trimethoprim is a derivative of Trimethoprim (T795615), an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. 4-O-Desmethyl 4-O-Ethyl Trimethoprim also has potential antibacterial activity.

4-O-DesMethyl 4-O-Ethyl TriMethopriM Preparation Products And Raw materials

Raw materials

Preparation Products

5-[(4-ethoxy-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine Trimethoprim EP Impurity G Trimethoprim Impurity 7 (Trimethoprim EP Impurity G) 5-(4-Ethoxy-3,5-dimethoxybenzyl)pyr 2,4-Pyrimidinediamine, 5-[(4-ethoxy-3,5-dimethoxyphenyl)methyl]- 5-(4-ethoxy-3,5-dimethoxybenzyl)pyrimidine-2,4-diamine 5-(4-Ethoxy-3,5-dimethoxybenzyl)pyrimidine-2,4-diamine (Trimethoprim Impurity) Methoxybenzene impurity G Methoxybenzyl impurity G 78025-68-0