2-(4-Isopropylpheny)-4H-chroMen-4-one

2-(4-Isopropylpheny)-4H-chroMen-4-one Structure
CAS No.
92831-11-3
Chemical Name:
2-(4-Isopropylpheny)-4H-chroMen-4-one
Synonyms
MN-64;MN64, >98%;MN64; MN 64;2-(4-Isopropyl-phenyl)-chromen-4-one;2-(4-Propan-2-ylphenyl)chromen-4-one;2-(4-Isopropylpheny)-4H-chroMen-4-one;2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-[4-(1-methylethyl)phenyl]-;MN-64,MN 64,poly ADP ribose polymerase,Inhibitor,PARP,inhibit;2-(4-Isopropyl pheny)-4H-chromen-4-one,(flavone, LXR agonist)
CBNumber:
CB72719624
Molecular Formula:
C18H16O2
Molecular Weight:
264.32
MOL File:
92831-11-3.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:20

2-(4-Isopropylpheny)-4H-chroMen-4-one Properties

Melting point 63-64 °C(Solv: ethanol (64-17-5))
Boiling point 389.8±42.0 °C(Predicted)
Density 1.152±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble20mg/mL, clear
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  Xn
Risk Statements  22
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
NFPA 704
0
2 0

2-(4-Isopropylpheny)-4H-chroMen-4-one Chemical Properties,Uses,Production

Uses

2-[4-(1-Methylethyl)phenyl4H-1-benzopyran-4-one is a potent and selective tankyrase (TNKS) inhibitor affecting cell proliferation with potential treatment for cancers. Flavonoid compound with anti-cancer/ anti-bacterial properties.

Biochem/physiol Actions

MN-64 is a very potent inhibitor of Tankyrase 1 and 2 (IC50 = 6 and 72 nM, respectively). The compound MN-64 blocks Wnt signaling in HEK293 cells containing a Wnt pathway reporter system.

2-(4-Isopropylpheny)-4H-chroMen-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

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92831-11-3(2-(4-Isopropylpheny)-4H-chroMen-4-one)Related Search:

MN-64 2-(4-Propan-2-ylphenyl)chromen-4-one 2-(4-Isopropylpheny)-4H-chroMen-4-one 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 2-[4-(1-methylethyl)phenyl]- MN64, >98% 2-(4-Isopropyl-phenyl)-chromen-4-one MN64; MN 64 2-(4-Isopropyl pheny)-4H-chromen-4-one,(flavone, LXR agonist) MN-64,MN 64,poly ADP ribose polymerase,Inhibitor,PARP,inhibit 92831-11-3