Molidustat(BAY 85-3934)

CAS No.: 1154028-82-6

Chemical Name:: Molidustat(BAY 85-3934)

Synonyms: CS-1728;Somatoprim;MOLIDUSTAT;BAY 85-3934;Molidustat(BAY 85-3934);BAY 85-3934;BAY-85-3934;2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(triazol-1-yl)-1H-pyrazol-3-one;2-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-3(2H)-one;1,2-dihydro-2-[6-(4-morpholinyl)-4-pyrimidinyl]-4-(1H-1,2,3-triazol-1-yl)-3H-pyrazol-3-one;2-[6-(4-Morpholinyl)-4-pyrimidinyl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one

CBNumber:: CB72729607

Molecular Formula:: C13H14N8O2

Molecular Weight:: 314.3

MOL File:: 1154028-82-6.mol

Modify Date:: 2024/7/2 8:55:16

Request For Quotation

Molidustat(BAY 85-3934) Properties

Boiling point	589.2±60.0 °C(Predicted)
Density	1.67±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	insoluble in EtOH; insoluble in H2O; ≥5.68 mg/mL in DMF
form	solid
pka	5.38±0.37(Predicted)
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS08,GHS07

Signal word

Danger

Hazard statements

H372-H360-H302

Precautionary statements

P264-P270-P301+P312-P330-P501-P260-P264-P270-P314-P501

NFPA 704

	0
2		0

Molidustat(BAY 85-3934) Chemical Properties,Uses,Production

Description

Hypoxia-inducible factor (HIF) is the major transcription factor involved in erythropoietin gene expression. Because oxygen-dependent degradation of the α subunit of HIF suppresses erythropoietin expression, stimulation of erythropoiesis by agents that prevent degradation of HIF has been one strategy for managing anemia. BAY 85-3934 stabilizes HIF from degradation in the proteasome by inhibiting HIF-1α prolyl hydroxylase (IC₅₀ = 0.49 μM). Inhibition of HIF prolyl hydroxylase by BAY 85-3934 has been shown to increase endogenous production of erythropoietin. This compound has been investigated in clinical trial for treatment of patients with anemia associated with chronic kidney disease and/or end-stage renal disease.

Molidustat(BAY 85-3934) Preparation Products And Raw materials

Raw materials

Preparation Products

Molidustat(BAY 85-3934) Suppliers

Global( 101)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32835	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29820	58	Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	China	5738	58	Inquiry
Wuhan Nutra Biotechnology Co.,Ltd	+8617786394783	China	300	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24738	58	Inquiry
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	China	3136	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Wuhan Nutra Biotechnology Co.,Ltd	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

Molidustat(BAY 85-3934) Spectrum

Molidustat(BAY 85-3934)(1154028-82-6)MS

1154028-82-6(Molidustat(BAY 85-3934))Related Search:

D-BETA-NAL-CYWKVCT-NH2 (DISULFIDE BRIDGE: 2-7) SOMATOSTATIN-25 AGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14), ACETATE SALT (LEU8,D-TRP22,TYR25)-SOMATOSTATIN 28 prosomatostatin

SOMATOSTATIN 28, CYCLIC SOMATOSTATIN-28 (1-12) SOMATOSTATIN-28 (1-14)

chevron_left

1of2

chevron_right

Molidustat(BAY 85-3934) BAY 85-3934 MOLIDUSTAT 2-[6-(4-Morpholinyl)-4-pyrimidinyl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one 2-[6-(Morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one Somatoprim 2-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-3(2H)-one 1,2-dihydro-2-[6-(4-morpholinyl)-4-pyrimidinyl]-4-(1H-1,2,3-triazol-1-yl)-3H-pyrazol-3-one BAY 85-3934;BAY-85-3934 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(triazol-1-yl)-1H-pyrazol-3-one CS-1728 3H-Pyrazol-3-one, 1,2-dihydro-2-[6-(4-morpholinyl)-4-pyrimidinyl]-4-(1H-1,2,3-triazol-1-yl)- 1154028-82-6 1154025-82-6 C13H14N8O2 Inhibitors API