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Voxelotor

Voxelotor Structure
CAS No.
1446321-46-5
Chemical Name:
Voxelotor
Synonyms
GBT 440;GTx011;Hemoglobin Modulators-1;2-Hydroxy-6-{[2-(1-isopropyl-1H-pyrazol-5-yl)-3-pyridinyl]methoxy}benzaldehyde;2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde;Oxbryta);Voxelotor;2H7]-Voxelotor;Voxelotor (GBT-440;GBT-440(Voxelotor)
CBNumber:
CB73053893
Molecular Formula:
C19H19N3O3
Molecular Weight:
337.37
MOL File:
1446321-46-5.mol
Modify Date:
2024/4/1 18:08:31
Request For Quotation

Voxelotor Properties

Melting point 95 - 97oC
Boiling point 539.2±50.0 °C(Predicted)
Density 1.23±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly)
pka 7.67±0.10(Predicted)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Voxelotor Chemical Properties,Uses,Production

Uses

GBT 440 is a potent allosteric effector of sickle cell hemoglobin (Hb) that increases the affinity of Hb for oxygen and inhibits its polymerization when subjected to hypoxic conditions.

Voxelotor Preparation Products And Raw materials

Raw materials

(2-Chloro-3-pyridinyl)methanol 1,3-bis(methoxymethoxy)benzaldehyde 2-hydroxy-6-(methoxymethoxy)benzaldehyde 3-(chloromethyl)-2-(1-isopropyl-1H-pyrazol-5-yl)pyridine hydrochloride [2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl]methanol
2-Bromoresorcinol 2,6-Dihydroxybenzaldehyde Resorcinol
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Preparation Products

Voxelotor Suppliers

Global( 111)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20327 58 Inquiry
Shaanxi TNJONE Pharmaceutical Co., Ltd +8618740459177 China 1142 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
Supplier Advantage
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Henan Fengda Chemical Co., Ltd 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 58
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
career henan chemical co 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Hefei TNJ Chemical Industry Co.,Ltd. 58

Related articles

2-hydroxy-6-([2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl]methoxy)benzaldehyde Voxelotor(GBT440, GTX011) Voxelotor Voxelotor, GBT-440, GBT 440, GBT440, GTx-011, GTx011, GTx 011 VOXELOTOR, GBT-440, GBT 440, GBT440, GTX-011, GTX011, GTX 011; GTX011;GTX011;GTX011 GBT-440(Voxelotor) Benzaldehyde, 2-hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]- Oxbryta) Voxelotor (GBT-440 Voxelotor,GBT440,GTX011,Hemoglobin Modulators-1 GBT 440 2-Hydroxy-6-{[2-(1-isopropyl-1H-pyrazol-5-yl)-3-pyridinyl]methoxy}benzaldehyde Hemoglobin Modulators-1 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde GTx011 2H7]-Voxelotor Lanreotide Impurity 33 2-Hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]benzaldehyde 1446321-46-5 API