(Z)-Guggulsterone
- CAS No.
- 95975-55-6
- Chemical Name:
- (Z)-Guggulsterone
- Synonyms
- GUGGULSTERONE;NSC 37445;Stersterone;GUGULSTERONE;GUGGULSTERONE Z;GUGGULESTERONES;GUGGULESTERONE Z;Coumarin sterone;CIS GUGGULSTERONE;Guggulsterone E&Z
- CBNumber:
- CB7309069
- Molecular Formula:
- C21H28O2
- Molecular Weight:
- 312.45
- MOL File:
- 95975-55-6.mol
- Modify Date:
- 2023/5/18 11:31:20
Boiling point | 463.3±45.0 °C(Predicted) |
---|---|
Density | 1.10±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: 5 mg/mL |
form | powder |
color | light yellow |
CAS DataBase Reference | 95975-55-6(CAS DataBase Reference) |
(Z)-Guggulsterone Chemical Properties,Uses,Production
Uses
Guggulsterone is a broad spectrum steroid receptor ligand. Gum resin of Commiphora mukul marketed as an antihyperlipidemic drug.
Biological Activity
Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (K i = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (K i values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR).
(Z)-Guggulsterone Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 175)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Apollo ingredients Pvt Ltd | +91-7219888886 | Maharashtra, India | 31 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Natural Remedy Private Limited | 09019202423 | Karnataka, India | 17 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3772 | 58 | Inquiry |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
95975-55-6((Z)-Guggulsterone)Related Search:
GUGGULSTERONE E
N-BUTYLISOCYANIDE
Tris(2,4-pentanedionato)chroMiuM(III)
COBALT(II) ACETYLACETONATE
TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
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4,17(20)-(CIS)-PREGNADIEN-3,16-DIONE
PREGNA-4,17(20)-DIENE-3,16-DIONE
(8S,9R,10R,13S,14S,17E)-17-(1-methoxyethylidene)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
pregna-4,17-diene-3,16-dione
GUGGULISTERONES 95%
CIS-4,17(20)-PREGNADIENE-3,16-DIONE
CIS GUGGULSTERONE
GUGULSTERONE
GUGGULSTERONE Z
GUGGULSTERONE (Z FORM)
GUGGULESTERONE Z
(17Z)-Pregna-4,17(20)-diene-3,16-dione
(17E)-Pregna-4,17(20)-diene-3,16-dione
GUGGULSTERONES E&Z(MIX)(FG)
GuggulsteronesE&Z(mix)
(E&Z)-Guggulsterone
Guggulsterone E&Z
Guggulsterones E&Z
(Z)-Guggulsterone
Guggulsterone E and Z
Stersterone
(Z)-Guggulsterone/Guggulsterone
GUGGULESTERONES
GUGGULSTERONE (GUGG),CAS:95975-55-6
NSC 37445
GUGGULSTERONE
Coumarin sterone
Guggulsterone(pregna-4,17-diene-3,16-dione)
(8R,9S,10R,13S,14S)-17-Ethylidene-10,13-dimethyl-7,8,9,10,11,12,13,14,15,17-decahydro-1H-cyclopenta[a]phenanthrene-3,16(2H,6H)-dione
95975-55-6
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