ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Thiophene compounds >2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE

2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE

2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE Structure
CAS No.
4815-28-5
Chemical Name:
2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
Synonyms
AURORA 971;AKOS B000691;AKOS BBB/013;AKOS MSC-0467;ASISCHEM V83886;AKOS BBS-00000705;CBI-BB ZERO/005481;TIMTEC-BB SBB000354;CHEMBRDG-BB 3000691;IFLAB-BB F0239-0077
CBNumber:
CB7328255
Molecular Formula:
C9H12N2OS
Molecular Weight:
196.27
MOL File:
4815-28-5.mol
MSDS File:
SDS
Modify Date:
2022/11/29 17:32:03

2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE Properties

Melting point 195-197℃
Boiling point 332.5±42.0 °C(Predicted)
Density 1.337±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 15.70±0.20(Predicted)
CAS DataBase Reference 4815-28-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  22
HazardClass  IRRITANT
NFPA 704
0
2 0

2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE Chemical Properties,Uses,Production

Hazard

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Synthesis

The synthesis of 2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE is as follows:
A solution of aminothiophene EO (prepared as described in Example C; 500mg, 2.8 mmol) in concentrated sulphuric acid (5ml) was stirred at room temperature for 65 hours. The reaction mixture was poured cautiously into ice-cold aqueous potassium carbonate, diluted with water and extracted with ethyl acetate. The combined organic extracts were washed with water and brine, dried over magnesium sulphate and evaporated to dryness under reduced pressure to give the desired product (383mg, 70%) as an off-white solid. 
synthesis of 2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE.png

2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE Preparation Products And Raw materials

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2-amino-4,5,6,7-tetrahydrobenzothiophene-3-carboxamide 2-azanyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide(SALTDATA: FREE) Benzo[b]thiophene-3-carboxaMide, 2-aMino-4,5,6,7-tetrahydro- 2-Amino-4,5,6,7-tetrahydro-1-benzo[b]thiophene-3-carboxamide TIMTEC-BB SBB000354 2-AMINO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE AKOS MSC-0467 AKOS BBS-00000705 AKOS BBB/013 AKOS B000691 1-BENZOTHIOPHENE-3-CARBOXAMIDE, 2-AMINO-4,5,6,7-TETRAHYDRO- 2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE 2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID AMIDE 2-AMINO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXAMIDE 2-AMINO-3-CARBOXAMIDO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE CBI-BB ZERO/005481 CHEMBRDG-BB 3000691 IFLAB-BB F0239-0077 AURORA 971 ASISCHEM V83886 ART-CHEM-BB B000691 4815-28-5 C9H12SN2O Sulphur Derivatives