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LOXO-195

LOXO-195 Structure
CAS No.
1350884-56-8
Chemical Name:
LOXO-195
Synonyms
LOXO-195;LOXO-195(3aR);(6RS)-LOXO-195;LOXO195 R racemic;Selitrectinib Racemate;Selitrectinib(LOXO-195) Racemate;(18bR)-17-Fluoro-1,2,3,11,12,13,14,18b-octahydro-12-methyl-10H-5,7-ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-10-one;12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR)-
CBNumber:
CB73311672
Molecular Formula:
C20H21FN6O
Molecular Weight:
380.42
MOL File:
1350884-56-8.mol
Modify Date:
2023/5/9 9:30:50
Request For Quotation

LOXO-195 Properties

Density 1.51±0.1 g/cm3(Predicted)
pka 11.44±0.40(Predicted)

LOXO-195 Chemical Properties,Uses,Production

Description

LOXO-195 is an orally available, highly potent, and selective TRK kinase inhibitor designed to overcome drug resistance mediated by acquired mutations. Although responses to TRK inhibition can be dramatic and durable; however, eventually emergence of acquired resistance is found to be inevitable.

LOXO-195 Preparation Products And Raw materials

Raw materials

Preparation Products

LOXO-195 Suppliers

Global( 44)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Hubei Ipure Biology Co., Ltd +8613367258412 China 10326 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology +undefined18143011203 China 42057 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Guangzhou Zhiya Chemdrugs Co.,Ltd 18122150900 China 646 55 Inquiry
Anqing Benro pharmachem Technology Co.,Ltd. 05565209906 15391842992 China 114 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 China 12308 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Hubei Ipure Biology Co., Ltd 58
AFINE CHEMICALS LIMITED 58
TargetMol Chemicals Inc. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
Amadis Chemical Company Limited 58
Guangzhou Zhiya Chemdrugs Co.,Ltd 55
Anqing Benro pharmachem Technology Co.,Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58

1350884-56-8(LOXO-195)Related Search:

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LOXO-195 LOXO195 R racemic 12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR)- Selitrectinib(LOXO-195) Racemate (6RS)-LOXO-195 Selitrectinib Racemate (18bR)-17-Fluoro-1,2,3,11,12,13,14,18b-octahydro-12-methyl-10H-5,7-ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-10-one LOXO-195(3aR) 1350884-56-8