EMBELIN
- CAS No.
- 550-24-3
- Chemical Name:
- EMBELIN
- Synonyms
- EMBELIN;emberine;NSC 91874;embelicacid;Embelin, >98%;XIAP INHIBITOR;EMbeliaquinone;TIMTEC-BB SBB005949;Embelin (Embelic acid);APOPTOSIS ACTIVATOR III
- CBNumber:
- CB7365074
- Molecular Formula:
- C17H26O4
- Molecular Weight:
- 294.39
- MOL File:
- 550-24-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/25 18:01:17
| Melting point | 142-143°C |
|---|---|
| Boiling point | 356.15°C (rough estimate) |
| Density | 1.131 |
| refractive index | 1.4230 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | DMSO: >10 mg/mL |
| form | solid |
| pka | 2.84±0.50(Predicted) |
| color | Dark orange |
| Sensitive | Light Sensitive |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
| LogP | 5.024 (est) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361f |
| Precautionary statements | P201-P308+P313 |
| WGK Germany | 3 |
| RTECS | DK4230000 |
EMBELIN price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | E1406 | Embelin ≥98% (HPLC), powder | 550-24-3 | 10MG | ₹9147.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E1406 | Embelin ≥98% (HPLC), powder | 550-24-3 | 50MG | ₹39381.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 178493 | Apoptosis Activator III, Embelin - CAS 550-24-3 - Calbiochem The Apoptosis Activator III, Embelin, also referenced under CAS 550-24-3, controls the biological activity of Apoptosis. This small molecule/inhibitor | 550-24-3 | 10MG | ₹17660.01 | 2022-06-14 | Buy |
| ALFA India | ALF-J64074-MF | Embelin | 550-24-3 | 50mg | ₹36711 | 2022-05-26 | Buy |
| ALFA India | ALF-J64074-MA | Embelin | 550-24-3 | 10mg | ₹9542 | 2022-05-26 | Buy |
EMBELIN Chemical Properties,Uses,Production
Chemical Properties
Orange Solid
Definition
ChEBI: A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, an ineoplastic and inhibitory activity towards hepatitis C protease.
Biological Activity
Cell-permeable, non-peptide inhibitor of X-linked inhibitor of apoptosis (XIAP) (IC 50 = 4.1 μ M in competition binding assay with Smac peptide); binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Inhibits cell growth, induces apoptosis and activates caspase-9 in prostate cancer cells (IC 50 4-6 μ M), but has a weaker effect on normal prostate cells (IC 50 = 19-20 μ M). Overcomes the protective effect of XIAP on apoptosis in XIAP-transfected Jurkat cells. Anti-tumor, analgesic and anti-inflammatory in vivo .
EMBELIN Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 188)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Natural Remedies Pvt Ltd | +91 (80) 4020-9999 | New Delhi, India | 110 | 50 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3777 | 58 | Inquiry |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2995 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
550-24-3(EMBELIN)Related Search:
EMBELIN
EMBELIN(P),EMBELIN(RG)
2-HYDROXY-5-METHOXY-3-PENTADECYL-[1,4]BENZOQUINONE
2-HYDROXY-5-METHOXY-3-UNDECYL-[1,4]BENZOQUINONE
2,5-DIHYDROXY-3-PENTADECYL-[1,4]BENZOQUINONE
ACETIC ACID 4-ACETOXY-3,6-DIOXO-5-UNDECYL-CYCLOHEXA-1,4-DIENYL ESTER
2-HYDROXY-5-METHOXY-3-TRIDECYL-[1,4]BENZOQUINONE
2,5-DIHYDROXY-3-METHYL-6-NONADECYL-[1,4]BENZOQUINONE
2,5-DIMETHOXY-3-METHYL-6-((E)-NONADEC-14-ENYL)-[1,4]BENZOQUINONE
2,5-DIMETHOXY-3-METHYL-6-NONADECYL-[1,4]BENZOQUINONE
chevron_left
1of4
chevron_right
2,5-dihydroxy-3-undecyl-p-benzoquinon
4-dione,2,5-dihydroxy-3-undecyl-5-cyclohexadiene-1
embelicacid
emberine
APOPTOSIS ACTIVATOR III
EMBELIN
2,5-DIHYDROXY-3-UNDECYL-1,4-BENZOQUINONE
2,5-DIHYDROXY-3-UNDECYL-2,5-CYCLOHEXADIENE-1,4-DIONE
2,5-DIHYDROXY-3-UNDECYL-P-BENZOQUINONE
TIMTEC-BB SBB005949
XIAP INHIBITOR
embelin from embelia seeds
2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3-undecyl- free base
EMbeliaquinone
2,5-DIHYDROXY-3-UNDECYL-P-BENZOQUINONE, EMBELIN
2,5-dihydroxy-3-undecyl-cyclohexa-2,5-diene-1,4-dione
2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione
NSC 91874
Apoptosis Activator III, Embelin
2,5-Cyclohexadiene-1,4-dione,2,5-dihydroxy-3-undecyl-
Embelin, >98%
Apoptosis Activator III, Embelin - CAS 550-24-3 - Calbiochem
Embelin (Embelic acid)
Embelin/Embelic Acid/NSC 91874
550-24-3
Antibiotics
Antibiotics A to Z
Antibiotics A-F
BioChemical
Inhibitors
Anthraquinones, Hydroquinones and Quinones
Caspases/Apoptosis