(4-BROMOPHENYL)[3-FLUORO-4-[[6-(METHYL-2-PROPENYLAMINO)HEXYL]OXY]PHENYL]-METHANONE
![(4-BROMOPHENYL)[3-FLUORO-4-[[6-(METHYL-2-PROPENYLAMINO)HEXYL]OXY]PHENYL]-METHANONE Structure](CAS/GIF/161582-11-2.gif)
- CAS No.
- 161582-11-2
- Chemical Name:
- (4-BROMOPHENYL)[3-FLUORO-4-[[6-(METHYL-2-PROPENYLAMINO)HEXYL]OXY]PHENYL]-METHANONE
- Synonyms
- RO 48-8071;(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl]methanone;(4-BROMOPHENYL)[3-FLUORO-4-[[6-(METHYL-2-PROPENYLAMINO)HEXYL]OXY]PHENYL]-METHANONE;Methanone, (4-broMophenyl)[2-fluoro-4-[[6-(Methyl-2-propenylaMino)hexyl]oxy]phenyl]-;Methanone, (4-bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]-
- CBNumber:
- CB7379585
- Molecular Formula:
- C23H27BrFNO2
- Molecular Weight:
- 448.37
- MOL File:
- 161582-11-2.mol
- Modify Date:
- 2023/6/8 9:03:08
Boiling point | 522.8±50.0 °C(Predicted) |
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Density | 1.235±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:2): .25 mg/ml |
pka | 8.88±0.50(Predicted) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS02,GHS07 |
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Signal word | Danger | |||||||||
Hazard statements | H225-H319-H336 | |||||||||
Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
NFPA 704 |
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(4-BROMOPHENYL)[3-FLUORO-4-[[6-(METHYL-2-PROPENYLAMINO)HEXYL]OXY]PHENYL]-METHANONE Chemical Properties,Uses,Production
Description
Oxidosqualene cyclase (OSC) is a microsomal enzyme that catalyzes the cyclization of monooxidosqualene to lanosterol in the cholesterol synthetic pathway. Ro 48-
Uses
Ro 48-8071 is an inhibitor of oxidosqualene cyclase.
Definition
ChEBI: An aromatic ketone that is 2-fluoro-4'-bromobenzophenone in which the hydrogen at position 4 (meta to the fluoro group) is replaced by a 6-[methyl(prop-2-en-1-yl)amino]hexyl}oxy group. An inhibitor of lanosterol synthase.
(4-BROMOPHENYL)[3-FLUORO-4-[[6-(METHYL-2-PROPENYLAMINO)HEXYL]OXY]PHENYL]-METHANONE Preparation Products And Raw materials
Raw materials
Preparation Products
(4-BROMOPHENYL)[3-FLUORO-4-[[6-(METHYL-2-PROPENYLAMINO)HEXYL]OXY]PHENYL]-METHANONE Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | China | 42057 | 58 | Inquiry |
TargetMol Chemicals Inc. | 15002134094 | China | 28118 | 58 | Inquiry |
Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | China | 40857 | 58 | Inquiry |
Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | China | 8740 | 58 | Inquiry |
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 | China | 10529 | 58 | Inquiry |
Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | China | 29803 | 58 | Inquiry |
Santa Cruz Biotechnology, Inc. | +1 (831) 457-3800 | United States | 3602 | 60 | Inquiry |
ApexBio Technology | + 1-832-696-8203 | United States | 6254 | 58 | Inquiry |