ChemicalBook > Product Catalog >Natural Products >Iridoid derivatives >LOGANIC ACID

LOGANIC ACID

LOGANIC ACID Structure
CAS No.
22255-40-9
Chemical Name:
LOGANIC ACID
Synonyms
Loganate;Norloganin;loganicaci;LOGANIC ACID;Margannic acid;LOGANIC ACID hplc;LOGANIC ACID WITH HPLC;Fluoroestradiol Impurity 37;Loganic acid >=95% (LC/MS-ELSD);Loganic acid, 98%, from Cornus officinalis Sieb. & Zucc.
CBNumber:
CB7384543
Molecular Formula:
C16H24O10
Molecular Weight:
376.36
MOL File:
22255-40-9.mol
Modify Date:
2023/5/25 18:01:17

LOGANIC ACID Properties

Boiling point 646.3±55.0 °C(Predicted)
Density 1.60±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in methan
form powder
pka 4.55±0.70(Predicted)
color White-beige
LogP -2.411 (est)

SAFETY

Risk and Safety Statements

WGK Germany  3

LOGANIC ACID price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SMB00231 Loganic acid ≥95% (LC/MS-ELSD) 22255-40-9 1MG ₹36545.2 2022-06-14 Buy
Product number Packaging Price Buy
SMB00231 1MG ₹36545.2 Buy

LOGANIC ACID Chemical Properties,Uses,Production

Description

Loganic acid is an iridoid glycoside that has been found in C. mas and has diverse biological activities, including antidiabetic, antiadipogenic, anti-atherosclerotic, and anti-inflammatory properties. Loganic acid (1 μM) stimulates glucagon-like peptide-1 (GLP-1) secretion by NCI H716 human enteroendocrine colorectal cancer cells. It inhibits dexamethasone-, 3-isobutyl-1-methylxanthine-, and insulin-induced differentiation of mouse 3T3-L1 fibroblasts into adipocytes when used at a concentration of 10 μg/ml. Loganic acid (20 mg/kg per day) decreases the plasma atherogenic index, a ratio of triglyceride to HDL cholesterol, and the cardiac risk ratio, a ratio of total cholesterol to HDL cholesterol, in a rabbit model of atherosclerosis induced by a cholesterol-rich diet. It also decreases IL-6, TNF-α, and oxidized LDL (oxLDL) plasma levels in the same model.

Definition

ChEBI: A cyclopentapyran that is 1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid substituted at positions 1, 6 and 7 by beta-D-glucosyloxy, hydroxy and methyl groups respectively

LOGANIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 205)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3424 58 Inquiry
Xi'an Kono chem co., Ltd., 029-86107037 13289246953 China 2995 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-519-519-85557386 China 12210 58 Inquiry
Hubei Ipure Biology Co., Ltd +8613367258412 China 10326 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry
Apeloa Pharmaceutical Co., Ltd. +86-0571-87635730 +8615858229168 China 1478 58 Inquiry

LOGANIC ACID Spectrum

LOGANIC ACID [1S-(1alpha,4aalpha,6alpha,7alpha,7aalpha)]-1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid (1S-(1alpha,4aalpha,6alpha,7alpha,7aalpha))-1-(beta-D-Glucopyranosylox y)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta(c)pyran-4-carb oxylic acid LOGANIC ACID hplc LOGANIC ACID WITH HPLC (1S)-1α-(β-D-Glucopyranosyloxy)-6α-hydroxy-7α-methyl-1,4aα,5,6,7,7aα-hexahydrocyclopenta[c]pyran-4-carboxylic acid [1S-(1a,4aa,6a,7a,7aa)]-1-(beta-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid [1S-(1α,4aα,6α,7α,7aα)]-1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid Loganate Norloganin Loganic acid, 98%, from Cornus officinalis Sieb. & Zucc. Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, (1S,4aS,6S,7R,7aS)- Loganic acid >=95% (LC/MS-ELSD) loganicaci [1S-(1α,4aα,6α,7α,7aα)]-1-(β-D-glucopyranosyloxy)-1,4a... Fluoroestradiol Impurity 37 (1S,4aS,6S,7R,7aS)-6-Hydroxy-7-methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid Margannic acid 22255-40-9 C16H24O10 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Iridoids