ISOGUVACINE HYDROCHLORIDE
- CAS No.
- 64603-90-3
- Chemical Name:
- ISOGUVACINE HYDROCHLORIDE
- Synonyms
- C13694;isoguvacine;ISOGUVACINE HCL;Isoguvacine hydrochl;ISOGUVACINE HYDROCHLORIDE;1,2,3,6-tetrahydro-4-Pyridinecarboxylic acid;ISOGUVACINE HYDROCHLORIDE ISO 9001：2015 REACH;4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-;1,2,3,6-TETRAHYDRO-4-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE;1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBOXYLIC ACIDHYDROCHLORIDE
- CBNumber:
- CB7406481
- Molecular Formula:
- C6H9NO2
- Molecular Weight:
- 127.14
- MOL File:
- 64603-90-3.mol
- Modify Date:
- 2023/5/4 17:34:41
| Melting point | 220 °C |
|---|---|
| Boiling point | 280.8±35.0 °C(Predicted) |
| Density | 1.199±0.06 g/cm3(Predicted) |
| RTECS | US5908286 |
| storage temp. | Store at RT |
| solubility | H2O: refrigerate if not used immediately.soluble |
| form | solid |
| pka | pK1:9.07 (25°C) |
| color | white |
| Water Solubility | Soluble in water |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
ISOGUVACINE HYDROCHLORIDE Chemical Properties,Uses,Production
Description
This base is isolated, together with Guvacine (q.v.) from the nuts of Areca catechu. It is optically inactive and yields crystalline salts: the hydrochloride, m.p. 231°C; aurich1oride, m.p. 198- 200°C and the p1atinich1oride, m.p. 235°C. The alkaloid is faintly acid to litmus and on methylation gives the N-methyl derivative which, on more vigorous methylation yields the dimethyl compound giving a crystalline platinichloride, m.p. 252°C. The above melting points suggest that the base may be mainly Arecaidine (q.v.) but on distillation with Zn dust, it yields products with the characteristic pyrrole reaction.
Chemical Properties
bp 195-197°C
Biological Activity
Specific GABA A receptor agonist.
References
Jahns., Ber., 21,3404 (1888) Jahns., ibid, 23, 2972 (1890) Jahns., ibid, 24,2615 (1891) Jahns., Arch. Pharrn., 229, 669 (1891) Trier., Zeit. Physiol. Chern., 85,372 (1913)
ISOGUVACINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
ISOGUVACINE HYDROCHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24639 | 58 | Inquiry |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
| Shanghai Weiwei Biological Technology Co., Ltd. | 021-55669583 18616258598 | CHINA | 4398 | 58 | Inquiry |
| Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
| Shanghai Haoyang Biological Technology Co., Ltd. | 021-54046790 15121098156 | CHINA | 2905 | 58 | Inquiry |
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