CALPHOSTIN C
![CALPHOSTIN C Structure](CAS/GIF/121263-19-2.gif)
- CAS No.
- 121263-19-2
- Chemical Name:
- CALPHOSTIN C
- Synonyms
- UCN-1028C;2-Diazole;PKF 115-584;CALPHOSTIN C;Cladochrome E;(R)-Calphostin C;Calphostin C,98%;He Ding C Carver;Calphostin CUCN-1028C;UCN 1028 C, PKF 115-384
- CBNumber:
- CB7457711
- Molecular Formula:
- C44H38O14
- Molecular Weight:
- 790.76
- MOL File:
- 121263-19-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
SAFETY
Risk and Safety Statements
Hazard Codes | Xn |
---|---|
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 24/25-36-26 |
WGK Germany | 3 |
HS Code | 29209010 |
CALPHOSTIN C price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C6303 | Calphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder | 121263-19-2 | 0.1MG | ₹36491.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C6303 | Calphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder | 121263-19-2 | 1MG | ₹235519.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 208725 | Calphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem A cell permeable, highly specific inhibitor of protein kinase C (IC?? = 50 nM) that interacts with the protein′s regulatory domain by competing at the | 121263-19-2 | 50μG | ₹14260 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 208725 | Calphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem A cell permeable, highly specific inhibitor of protein kinase C (IC?? = 50 nM) that interacts with the protein′s regulatory domain by competing at the | 121263-19-2 | 100μG | ₹23839.99 | 2022-06-14 | Buy |
CALPHOSTIN C Chemical Properties,Uses,Production
Chemical Properties
Dark red solid
Uses
Calphostin C (CGP049090) is a perylenequinione isolated from the fungus, Cladosporium cladosporioides. Calphostin C is a potent and specific inhibitor of protein kinase C (PKC), with inhibition being light dependent. Calphostin C inhibits cell proliferation and induces apoptosis in vitro. Calphostin C is an antagonist of Tcf4/b-catenin signalling, inhibiting the expression of survivin and inducing apoptosis in several tumour cell lines.
Biological Activity
Potent, selective and photo-dependent inhibitor of protein kinase C that targets the regulatory domain (IC 50 = 50 nM). Displays > 1000-fold selectivity over other protein kinases such as cAMP-dependent protein kinase and tyrosine-specific protein kinase. Inhibits cell proliferation of malignant glioma cells in light-treated conditions in vitro (IC 50 ~ 40-60 nM).
CALPHOSTIN C Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30250 | 58 | Inquiry |
BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | China | 30968 | 58 | Inquiry |
Nantong Tianxiang Bioengineering Co., Ltd | 0513-5666452 4006716686 | China | 1073 | 58 | Inquiry |
Shandong Yatu Biotechnology Co. LTD | 0531-55555418 15301096991 | China | 1106 | 58 | Inquiry |