CALPHOSTIN C

CAS No.: 121263-19-2

Chemical Name:: CALPHOSTIN C

Synonyms: UCN-1028C;2-Diazole;PKF 115-584;CALPHOSTIN C;Cladochrome E;(R)-Calphostin C;Calphostin C,98%;He Ding C Carver;Calphostin CUCN-1028C;UCN 1028 C, PKF 115-384

CBNumber:: CB7457711

Molecular Formula:: C44H38O14

Molecular Weight:: 790.76

MOL File:: 121263-19-2.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

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CALPHOSTIN C Properties

Boiling point	1039.8±65.0 °C(Predicted)
Density	1.48±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMF: 1 mg/mL
form	powder
pka	7.30±0.20(Predicted)
color	red to brown

SAFETY

Risk and Safety Statements

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	24/25-36-26
WGK Germany	3
HS Code	29209010

CALPHOSTIN C price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	C6303	Calphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder	121263-19-2	0.1MG	₹36491.08	2022-06-14	Buy
Sigma-Aldrich(India)	C6303	Calphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder	121263-19-2	1MG	₹235519.53	2022-06-14	Buy
Sigma-Aldrich(India)	208725	Calphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem A cell permeable, highly specific inhibitor of protein kinase C (IC?? = 50 nM) that interacts with the protein′s regulatory domain by competing at the	121263-19-2	50μG	₹14260	2022-06-14	Buy
Sigma-Aldrich(India)	208725	Calphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem A cell permeable, highly specific inhibitor of protein kinase C (IC?? = 50 nM) that interacts with the protein′s regulatory domain by competing at the	121263-19-2	100μG	₹23839.99	2022-06-14	Buy

Product number	Packaging	Price	Buy
C6303	0.1MG	₹36491.08	Buy
C6303	1MG	₹235519.53	Buy
208725	50μG	₹14260	Buy
208725	100μG	₹23839.99	Buy

CALPHOSTIN C Chemical Properties,Uses,Production

Chemical Properties

Dark red solid

Uses

Calphostin C (CGP049090) is a perylenequinione isolated from the fungus, Cladosporium cladosporioides. Calphostin C is a potent and specific inhibitor of protein kinase C (PKC), with inhibition being light dependent. Calphostin C inhibits cell proliferation and induces apoptosis in vitro. Calphostin C is an antagonist of Tcf4/b-catenin signalling, inhibiting the expression of survivin and inducing apoptosis in several tumour cell lines.

Biological Activity

Potent, selective and photo-dependent inhibitor of protein kinase C that targets the regulatory domain (IC 50 = 50 nM). Displays > 1000-fold selectivity over other protein kinases such as cAMP-dependent protein kinase and tyrosine-specific protein kinase. Inhibits cell proliferation of malignant glioma cells in light-treated conditions in vitro (IC 50 ~ 40-60 nM).

CALPHOSTIN C Preparation Products And Raw materials

Raw materials

Preparation Products

CALPHOSTIN C Suppliers

Global( 105)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30250	58	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24738	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
Nantong Hanfang Biotechnology Co. , Ltd.	18616537568	China	30968	58	Inquiry
Nantong Tianxiang Bioengineering Co., Ltd	0513-5666452 4006716686	China	1073	58	Inquiry
Shandong Yatu Biotechnology Co. LTD	0531-55555418 15301096991	China	1106	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
BOC Sciences	58
LEAP CHEM CO., LTD.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Nantong Hanfang Biotechnology Co. , Ltd.	58
Nantong Tianxiang Bioengineering Co., Ltd	58
Shandong Yatu Biotechnology Co. LTD	58

121263-19-2(CALPHOSTIN C)Related Search:

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1,2-DIMETHYLNAPHTHALENE 2-Naphthaleneethanol 2-HYDROXY-1-NAPHTHALDEHYDE Divinylbenzene calphostin B

7-METHYL-2-NAPHTHOL 1-Naphthalenol,6-methyl-(9CI) 1,8-DIMETHYLPHENANTHRENE

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CALPHOSTIN C CALPHOSTIN C FROM CLADOSPORIUMCLADOSPORI OIDES UCN-1028C (R)-Calphostin C 1-[(R)-2-(4-Hydroxyphenoxycarbonyloxy)propyl]-2,6,7,11-tetramethoxy-4,9-dihydroxy-12-[(R)-2-(benzoyloxy)propyl]-3,10-dihydroperylene-3,10-dione 4,9-Dihydroxy-12-[(R)-2-(4-hydroxyphenyloxy)carbonyloxypropyl]-2,6,7,11-tetramethoxy-1-[(R)-2-benzoyloxypropyl]perylene-3,10-dione Calphostin C,98% Calphostin CUCN-1028C (1R)-2-[12-[(2R)-2-(Benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethylcarbonicacid4-hydroxyphenylester Calphostin C(UCN 1028C, PKF 115584) C,CalphostinCfroMCladosporiuMcladosporioide CALPHOSTIN C, CLADOSPORIUM CLADOSPORIOIDES 2-[12-[2-(BENZOYLOXY)PROPYL]-3,10-DIHYDRO-4,9-DIHYDROXY-2,6,7,11-TETRAMETHOX Y-3,10-DIOXO-1-PERYLENYL]-1-METHYLETHYL CARBONIC ACID 4-HYDROXYPHENYL ESTER UCN 1028 C, PKF 115-384 Cladochrome E PKF 115-584 He Ding C Carver Carbonic acid,(1R)-2-[12-[(2R)-2-(benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethyl4-hydroxyphenyl ester, stereoisomer Calphostin C, 95.0+ % (HPLC) (1R)-2-[12-[(2R)-2-(benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethyl 4-carbonic Calphostin C DISCONTINUED 2-Diazole 121263-19-2 C44H38O14 Kinase/Phosphatase Biology Serine/Threonine Kinase Inhibitors Protein Kinase C (PKC) BioChemical Cell Biology Cell Signaling and Neuroscience