NS-398
- CAS No.
- 123653-11-2
- Chemical Name:
- NS-398
- Synonyms
- NS NS;NS-398;CS-2231;NS-398 98%;Taisho NS 398;NS-398 (NS 398;NS-398 USP/EP/BP;NS-398 - CAS 123653-11-2 - Calbiochem;Inhibitor,inhibit,NS-398,NS 398,COX,Cyclooxygenase;N-[2-(cyclohexoxy)-4-nitro-phenyl]methanesulfonamide
- CBNumber:
- CB1754593
- Molecular Formula:
- C13H18N2O5S
- Molecular Weight:
- 314.36
- MOL File:
- 123653-11-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/22 17:12:53
| Melting point | 124-126 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
|---|---|
| Boiling point | 490.6±55.0 °C(Predicted) |
| Density | 1.377±0.06 g/cm3(Predicted) |
| RTECS | PB0473500 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: >5 mg/mL |
| form | solid |
| pka | 6.33±0.10(Predicted) |
| color | off-white |
NS-398 price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N194 | NS-398 ≥98% (HPLC), solid | 123653-11-2 | 5MG | ₹24735.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N194 | NS-398 ≥98% (HPLC), solid | 123653-11-2 | 25MG | ₹97035.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 349254 | NS-398 - CAS 123653-11-2 - Calbiochem A cell-permeable selective inhibitor of COX-2 in vitro. | 123653-11-2 | 5MG | ₹17860 | 2022-06-14 | Buy |
| TCI Chemicals (India) | N1152 | NS-398 | 123653-11-2 | 10MG | ₹6300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | N1152 | NS-398 | 123653-11-2 | 50MG | ₹14200 | 2022-05-26 | Buy |
NS-398 Chemical Properties,Uses,Production
Description
NS-
Uses
NS-398 is a selective Cox-2 inhibitor neuroprotective agent.
Definition
ChEBI: A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.
Biological Activity
Selective cyclooxygenase-2 inhibitor (IC 50 values are 3.8 and > 100 μ M for COX-2 and COX-1 respectively). Induces apoptosis in colorectal tumor cells and elevates COX-2 protein expression in vitro . Orally active and non-ulcerogenic analgesic and anti-inflammatory in vivo .
NS-398 Preparation Products And Raw materials
Global( 149)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12447 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5873 | 58 | Inquiry |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | China | 973 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30250 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24200 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
123653-11-2(NS-398)Related Search:
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NS-398
N-[2-(CYCLOHEXYLOXY)-4-NITROPHENYL]-METHANESULFONAMIDE
NS-398 98%
N-[2-(cyclohexoxy)-4-nitro-phenyl]methanesulfonamide
Taisho NS 398
CS-2231
NS-398 (NS 398
NS-398 - CAS 123653-11-2 - Calbiochem
NS 398; NS398; N-(2-CYCLOHEXYLOXY-4-NITROPHENYL)METHANE SULFONAMIDE
NS NS
Methanesulfonamide, N-[2-(cyclohexyloxy)-4-nitrophenyl]-
NS-398 USP/EP/BP
Inhibitor,inhibit,NS-398,NS 398,COX,Cyclooxygenase
123653-11-2
123652-11-2
Cyclooxygenase (COX) Enzymes
Cyclooxygenase Inhibitors
Enzymes, Inhibitors, and Substrates
Biochemicals and Reagents
Cell Signaling Enzymes
BioChemical
Application Index
Signalling
Lipid signaling
NF-κB Signaling