Potassium clavulanate
- CAS No.
- 61177-45-5
- Chemical Name:
- Potassium clavulanate
- Synonyms
- CLAVULANATE POTASSIUM;Clavulanate;Potassium Clavulanat;potassium calvulanate;Potassium clavulanate USP/EP/BP;MM 1415;Amonate;brl14151k;Clavulanate K;CLAVULANTE POTASSIUM
- CBNumber:
- CB2722502
- Molecular Formula:
- C8H10KNO5
- Molecular Weight:
- 239.27
- MOL File:
- 61177-45-5.mol
- Modify Date:
- 2024/8/24 19:19:26
| Melting point | >1600C (dec) |
|---|---|
| alpha | +55～+60° |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Freely soluble in water, slightly soluble in ethanol (96 per cent), very slightly soluble in acetone. |
| form | Solid |
| color | Light brown to brown |
| InChIKey | ABVRVIZBZKUTMK-JSYANWSFSA-M |
| CAS DataBase Reference | 61177-45-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H228-H252-H317-H334 | |||||||||
| Precautionary statements | P210-P235-P280-P302+P352-P304+P340+P312-P403+P235 | |||||||||
| Hazard Codes | F,Xn,Xi | |||||||||
| Risk Statements | 11-42/43-44-36-14 | |||||||||
| Safety Statements | 8-16-22-36/37-45-43-26 | |||||||||
| RIDADR | UN1325 - class 4.1 - PG 2 - Flammable solids, organic, n.o.s., HI: all | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | RN6802700 | |||||||||
| HS Code | 2941900000 | |||||||||
| NFPA 704 |
|
Potassium clavulanate Chemical Properties,Uses,Production
Description
Clavulanate is a β-lactamase inhibitor that is effective against Ambler class A β-lactamases (IC50 values range from 12 to 60 nM). While it is not an effective antibiotic by itself, clavulanate is commonly used with other antibiotics that would be inactivated by β-lactamases secreted by bacteria. It is often combined with amoxicillin and other penicillin-based antibiotics.
Chemical Properties
Pale Yellowish Solid
Uses
A -Lactamase inhibitor, typically added to amoxicillin to increase its effectiveness
Definition
ChEBI: A potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes and has only weak anitbiotic activity when administered alone. However it can be used in combination with amoxicillin trihydrate (under the trade name Augmentin) for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases.
Potassium clavulanate Preparation Products And Raw materials
Raw materials
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61177-45-5(Potassium clavulanate)Related Search:
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CLAVULANIC ACID POTASSIUM
CLAVULANIC ACID POTASSIUM SALT
CLAVULANTE POTASSIUM
MM 1415
4-Oxa-1-azabicyclo3.2.0heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, (2R,3Z,5R)-
POTASSIUMCLAVULANATE,EP
4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, (2R,3Z,5R)- (9CI)
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clavulanate,potassium salt
CLAVULANIC ACID POTASSIUM SALT (POTASSIUM CLAVULANATE)/AVICEL (1:1)
Clavulanate K
Clavulanic acid potassium salt (Potassium Clavulanate)/Avicel (1
Clavulanate:Cellulose
Clavulanic acid Potassium salt:Cellulose (1:1)
Clavulanate PotassiuMAvicel API
CLAVULANATE POTASSIUM +AVICE
potassiuM (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
ClavubactaM potassiuM, BRL 14151
Clavullinate PotassiuM USP
Microcrystalline cellulose (1:1)
potassium clavulanate sterile
POTASSIUM CLAVULANATE
potassium (z)-(2r,5r)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
brl14151k
monopotassiumsalt,(2r-(2-alpha,3z,5-alpha))-xo
CLAVULANIC POTASSIUM
potassium [2R-(2alpha,3Z,5alpha)]-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
POTASSIUM CLAVULANATE FROM STREPTOMYCES
4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, potassium salt (1:1), (2R,3Z,5R)-
Amonate
Clavaulanate Potassium with
Microcrystalline Cellulose 1:1
Amoxicillin with Clavulanate Potassium 4:1
Trihydrate with Clavanate Potassium 4:1
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Sterile Clavulanate Potassium+Amoxicillin
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CLAVULANATE POTASSIUM
Potassium Clavulanat
Clavulanate
potassium calvulanate
Potassium clavulanate USP/EP/BP
2,2′-(oxybismethylene)bis[2-(hydroxymethyl)propane-1,3-diol]hexanitrate(dipentaerythritylhexanitrate).
Amoxicillin and Clavulanate Potassium: 1: 1
61177-45-5
C8H8NO5K
C8H8KNO5
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