Potassium clavulanate
![Potassium clavulanate Structure](CAS/GIF/61177-45-5.gif)
- CAS No.
- 61177-45-5
- Chemical Name:
- Potassium clavulanate
- Synonyms
- CLAVULANATE POTASSIUM;Clavulanate;Potassium Clavulanat;potassium calvulanate;Potassium clavulanate USP/EP/BP;MM 1415;Amonate;brl14151k;Clavulanate K;CLAVULANTE POTASSIUM
- CBNumber:
- CB2722502
- Molecular Formula:
- C8H10KNO5
- Molecular Weight:
- 239.27
- MOL File:
- 61177-45-5.mol
- Modify Date:
- 2024/8/24 19:19:26
Melting point | >1600C (dec) |
---|---|
alpha | +55~+60° |
storage temp. | Inert atmosphere,2-8°C |
solubility | Freely soluble in water, slightly soluble in ethanol (96 per cent), very slightly soluble in acetone. |
form | Solid |
color | Light brown to brown |
InChIKey | ABVRVIZBZKUTMK-JSYANWSFSA-M |
CAS DataBase Reference | 61177-45-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS02,GHS08 |
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Signal word | Danger | |||||||||
Hazard statements | H228-H252-H317-H334 | |||||||||
Precautionary statements | P210-P235-P280-P302+P352-P304+P340+P312-P403+P235 | |||||||||
Hazard Codes | F,Xn,Xi | |||||||||
Risk Statements | 11-42/43-44-36-14 | |||||||||
Safety Statements | 8-16-22-36/37-45-43-26 | |||||||||
RIDADR | UN1325 - class 4.1 - PG 2 - Flammable solids, organic, n.o.s., HI: all | |||||||||
WGK Germany | 2 | |||||||||
RTECS | RN6802700 | |||||||||
HS Code | 2941900000 | |||||||||
NFPA 704 |
|
Potassium clavulanate Chemical Properties,Uses,Production
Description
Clavulanate is a β-lactamase inhibitor that is effective against Ambler class A β-lactamases (IC50 values range from 12 to 60 nM). While it is not an effective antibiotic by itself, clavulanate is commonly used with other antibiotics that would be inactivated by β-lactamases secreted by bacteria. It is often combined with amoxicillin and other penicillin-based antibiotics.
Chemical Properties
Pale Yellowish Solid
Uses
A -Lactamase inhibitor, typically added to amoxicillin to increase its effectiveness
Definition
ChEBI: A potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes and has only weak anitbiotic activity when administered alone. However it can be used in combination with amoxicillin trihydrate (under the trade name Augmentin) for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases.
Potassium clavulanate Preparation Products And Raw materials
Raw materials
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Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | China | 2503 | 58 | Inquiry |
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