ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Tyrosine derivatives >AG 490
AG 490
- CAS No.
- 134036-52-5
- Chemical Name:
- AG 490
- Synonyms
- AG 490;(E/Z)-AG490;TYRPHOSTIN B42;AG 490 USP/EP/BP;TYROPHOSTIN AG490;TYRPHOSTIN AG 490;(E/Z)-Tyrphostin B42;AG 490, Tryphostin B42;(E/Z)-Tyrphostin AG490;TYRPHOSTIN AG 490, 99+%
- CBNumber:
- CB7779213
- Molecular Formula:
- C17H14N2O3
- Molecular Weight:
- 294.3
- MOL File:
- 134036-52-5.mol
- Modify Date:
- 2023/5/18 11:31:18
| Melting point | 215 |
|---|---|
| Boiling point | 615.2±55.0 °C(Predicted) |
| Density | 1.337±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | ethanol: 5 mg/mL |
| pka | 8.82±0.35(Predicted) |
| form | solid |
| color | yellow |
| CAS DataBase Reference | 134036-52-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-50-25 |
| Safety Statements | 26-36-61-45 |
| WGK Germany | 1 |
| Hazard Note | Irritant/Keep Cold under -20C |
| HS Code | 2926907090 |
AG 490 Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow-Green Crystal
Uses
A potent and specific inhibitor of the Jak-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. AG-490 is cell permeable and is active in vivo.
AG 490 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 148)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24639 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | China | 25363 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
| Hongtuo Biotechnology Co., Ltd. | 0571-88760729 | CHINA | 697 | 58 | Inquiry |
| Shenzhen Xinbosheng Biological Technology Co., Ltd. | 0755-26755892 | CHINA | 6164 | 58 | Inquiry |
| Beijing Anbiqi Biotechnology Co., Ltd. | 15811277462 | CHINA | 2529 | 58 | Inquiry |
| Guangzhou Weijia Technology Co., Ltd. | 020-84224925 18300190102 | CHINA | 6748 | 58 | Inquiry |
134036-52-5(AG 490)Related Search:
AG 490, Tryphostin B42
2-Cyano-3-(3,4-dihydroxyphenyl)-N-benzylacrylamide
N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)propenamide
TYRPHOSTIN AG 490
TYROPHOSTIN AG490
TYRPHOSTIN B42
TYRPHOSTIN AG 490, 99+%
N-Benzyl-2-(3,4-dihydroxybenzylidene)-2-cyanoacetamide
(E)-2-CYANO-3-(3,4-DIHYDROPHENYL)-N-(PHENYLMETHYL)-2-PROPENAMIDE
ALPHA-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE
AG 490
A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMAMIDE
A-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE
2-CYANO-3-[3,4-DIHYDROXYPHENYL]-N-[PHENYLMETHYL]-2-PROPENAMIDE
N-BENZYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMIDE
N-BENZYL-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE
(E/Z)-Tyrphostin B42
(E/Z)-Tyrphostin AG490
(E/Z)-AG490
AG 490 USP/EP/BP
2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-
134036-52-5
34036-52-5
Cell Signaling and Neuroscience
Cell Biology
BioChemical
Kinase/Phosphatase Biology
Janus Kinase (JAK)
Non-Receptor Tyrosine Kinase Inhibitors
Inhibitor
Aromatics
Intermediates & Fine Chemicals
Pharmaceuticals
All Inhibitors
Inhibitors
Tyrosine Kinase Inhibitors