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AG 18
![AG 18 Structure](CAS/GIF/118409-57-7.gif)
- CAS No.
- 118409-57-7
- Chemical Name:
- AG 18
- Synonyms
- AG 18;TX 825;CS-931;RG-50810;RG 50858;AG18, >=98%;TYRPHOSTIN 23;TYRPHOSTIN A23;Tyrphostin AG 1;AG-18(RG-50810)
- CBNumber:
- CB2358507
- Molecular Formula:
- C10H6N2O2
- Molecular Weight:
- 186.17
- MOL File:
- 118409-57-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:34
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Warning |
Hazard statements | H371-H373 |
Precautionary statements | P501-P260-P270-P264-P308+P311-P405 |
WGK Germany | 3 |
HS Code | 2926.90.5050 |
AG 18 price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | T7165 | Tyrphostin 23 ≥98% | 118409-57-7 | 5MG | ₹12676.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T7165 | Tyrphostin 23 ≥98% | 118409-57-7 | 25MG | ₹49091.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 658395 | AG 18 - CAS 118409-57-7 - Calbiochem A broad-spectrum protein tyrosine kinase inhibitor. | 118409-57-7 | 5MG | ₹9490 | 2022-06-14 | Buy |
ALFA India | ALF-J60308-MB | Tyrphostin A23, 99% | 118409-57-7 | 25mg | ₹29743 | 2022-05-26 | Buy |
TCI Chemicals (India) | T3503 | Tyrphostin A23 min. 98.0 % | 118409-57-7 | 25MG | ₹8800 | 2022-05-26 | Buy |
AG 18 Chemical Properties,Uses,Production
Chemical Properties
Yellow Powder
Uses
AG 18 inhibits EGFR with IC50 of 35 μM.
Biological Activity
Inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC 50 values are 35 and 25 μ M respectively). Inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler that alters phosphorylation-dependent cell signaling.
AG 18 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 160)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29892 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24330 | 58 | Inquiry |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
118409-57-7(AG 18)Related Search:
RARECHEM AL BX 0069
RG-50810
TYRPHOSTIN RG 50858
TYRPHOSTIN AG 18
TYRPHOSTIN A23
TYRPHOSTIN 23
ALPHA-CYANO-(3,4-DIHYDROXY)CINNAMONITRILE
AG 18
[3,4-DIHYDROXYBENZYLIDENE]MALONONITRILE
[(3,4-DIHYDROXYPHENYL)METHYLENE]-PROPENEDINITRILE
TYRPHOSTIN A23 99+%
(3,4-Dihydroxybenzylidene)-malononitrile, RG-50810
AG 18 (Tyrphostin A23)
2-(3,4-Dihydroxyphenyl)ethene-1,1-dicarbonitrile
4,5-Dihydroxybenzylidenemalononitrile
(3,4-Dihydroxyphenyl)methylene propanedinitrile
Propanedinitrile, ((3,4-dihydroxyphenyl)methylene)-
AG 18 (Tyrphostin 23)
2-(3,4-Dihydroxybenzylidene)malononitrile
AG 18 (pharmaceutical)
RG 50858
TX 825
TYRPHOSTIN 23;AG 18; AG-18; AG18
Propanedinitrile, 2-[(3,4-dihydroxyphenyl)methylene]-
AG 18 (3,4-Dihydroxybenzylidene)malononitrile 2-(3,4-Dihydroxybenzylidene)malononitrile
Tyrphostin AG 1
α-Cyano-(3,4-dihydroxy)cinnamonitrile 
AG-18(RG-50810)
α-Cyano-(3,4-dihydroxy)cinnamonitrile
AG18, >=98%
AG18,RG-50810, Tyrphostin A23, >98%
AG 18 - CAS 118409-57-7 - Calbiochem
RG-50810; TYRPHOSTIN A23; AG-18; AG18; RG 50810; RG50810
CS-931
AG 18 (Tyrphostin 23, RG-50810)
2-[(3,4-Dihydroxyphenyl)methylidene]propanedinitrile
AG 18 USP/EP/BP
AG18,RG-50810, Tyrphostin A23
AG-18 (RG50858, TX-825)
Tyrphostin A23 AG18
Tyrphostin 23,inhibit,RG 50810,EGFR,Inhibitor,HER1,Tyrphostin23,AG-18,AG 18,Epidermal growth factor receptor,RG50810,Tyrphostin A 23,Tyrphostin A-23,ErbB-1,Tyrphostin-23
118409-57-7
C10H6N2O2
BioChemical
Cell Biology
Cell Signaling and Neuroscience
Kinase/Phosphatase Biology
Receptor Tyrosine Kinase Inhibitors
Epidermal Growth Factor Receptor (EGFR)
Intracellular Signaling
Protein Kinase
All Inhibitors
Inhibitors
Tyrosine Kinase Inhibitors