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AG 18

CAS No.: 118409-57-7

Chemical Name:: AG 18

Synonyms: AG 18;TX 825;CS-931;RG-50810;RG 50858;AG18, >=98%;TYRPHOSTIN 23;TYRPHOSTIN A23;Tyrphostin AG 1;AG-18(RG-50810)

CBNumber:: CB2358507

Molecular Formula:: C10H6N2O2

Molecular Weight:: 186.17

MOL File:: 118409-57-7.mol

MSDS File:: SDS

Modify Date:: 2023/6/8 17:06:34

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AG 18 Properties

Melting point	225°C
Boiling point	421.1±45.0 °C(Predicted)
Density	1.428±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in DMSO, ethanol, or DMF
pka	7.26±0.18(Predicted)
form	Yellow solid
color	Yellow
λmax	464nm(DMSO)(lit.)
Stability	Store in refrigerator

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H371-H373
Precautionary statements	P501-P260-P270-P264-P308+P311-P405
WGK Germany	3
HS Code	2926.90.5050

AG 18 price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	T7165	Tyrphostin 23 ≥98%	118409-57-7	5MG	₹12676.08	2022-06-14	Buy
Sigma-Aldrich(India)	T7165	Tyrphostin 23 ≥98%	118409-57-7	25MG	₹49091.38	2022-06-14	Buy
Sigma-Aldrich(India)	658395	AG 18 - CAS 118409-57-7 - Calbiochem A broad-spectrum protein tyrosine kinase inhibitor.	118409-57-7	5MG	₹9490	2022-06-14	Buy
ALFA India	ALF-J60308-MB	Tyrphostin A23, 99%	118409-57-7	25mg	₹29743	2022-05-26	Buy
TCI Chemicals (India)	T3503	Tyrphostin A23 min. 98.0 %	118409-57-7	25MG	₹8800	2022-05-26	Buy

Product number	Packaging	Price	Buy
T7165	5MG	₹12676.08	Buy
T7165	25MG	₹49091.38	Buy
658395	5MG	₹9490	Buy
ALF-J60308-MB	25mg	₹29743	Buy
T3503	25MG	₹8800	Buy

AG 18 Chemical Properties,Uses,Production

Chemical Properties

Yellow Powder

Uses

AG 18 inhibits EGFR with IC50 of 35 μM.

Biological Activity

Inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC 50 values are 35 and 25 μ M respectively). Inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler that alters phosphorylation-dependent cell signaling.

AG 18 Preparation Products And Raw materials

Raw materials

Preparation Products

AG 18 Suppliers

Global( 160)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6913	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29892	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	24330	58	Inquiry
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	China	52861	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
TCI Chemicals (India) Pvt. Ltd.	58
Alfa Aesar	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58

AG 18 Spectrum

AG 18(118409-57-7)¹HNMR

118409-57-7(AG 18)Related Search:

TYRPHOSTIN A25 AG 213 TYRPHOSTIN AG 126 2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, (2E)- (9CI) TYRPHOSTIN AG 835

AG 99 TYRPHOSTIN A9 AG 1295 4-HYDROXYBENZYLIDENEMALONONITRILE 4-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-ylamino)phenol

Tyrphostin AG1433 TYRPHOSTIN A1 TYRPHOSTIN AG 1296 XL999 TYRPHOSTIN AG 528

TYRPHOSTIN AG 1288 AG 18 NS-398

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RARECHEM AL BX 0069 RG-50810 TYRPHOSTIN RG 50858 TYRPHOSTIN AG 18 TYRPHOSTIN A23 TYRPHOSTIN 23 ALPHA-CYANO-(3,4-DIHYDROXY)CINNAMONITRILE AG 18 [3,4-DIHYDROXYBENZYLIDENE]MALONONITRILE [(3,4-DIHYDROXYPHENYL)METHYLENE]-PROPENEDINITRILE TYRPHOSTIN A23 99+% (3,4-Dihydroxybenzylidene)-malononitrile, RG-50810 AG 18 (Tyrphostin A23) 2-(3,4-Dihydroxyphenyl)ethene-1,1-dicarbonitrile 4,5-Dihydroxybenzylidenemalononitrile (3,4-Dihydroxyphenyl)methylene propanedinitrile Propanedinitrile, ((3,4-dihydroxyphenyl)methylene)- AG 18 (Tyrphostin 23) 2-(3,4-Dihydroxybenzylidene)malononitrile AG 18 (pharmaceutical) RG 50858 TX 825 TYRPHOSTIN 23;AG 18; AG-18; AG18 Propanedinitrile, 2-[(3,4-dihydroxyphenyl)methylene]- AG 18 (3,4-Dihydroxybenzylidene)malononitrile 2-(3,4-Dihydroxybenzylidene)malononitrile Tyrphostin AG 1 α-Cyano-(3,4-dihydroxy)cinnamonitrile AG-18(RG-50810) α-Cyano-(3,4-dihydroxy)cinnamonitrile AG18, >=98% AG18,RG-50810, Tyrphostin A23, >98% AG 18 - CAS 118409-57-7 - Calbiochem RG-50810; TYRPHOSTIN A23; AG-18; AG18; RG 50810; RG50810 CS-931 AG 18 (Tyrphostin 23, RG-50810) 2-[(3,4-Dihydroxyphenyl)methylidene]propanedinitrile AG 18 USP/EP/BP AG18，RG-50810， Tyrphostin A23 AG-18 (RG50858, TX-825) Tyrphostin A23 AG18 Tyrphostin 23,inhibit,RG 50810,EGFR,Inhibitor,HER1,Tyrphostin23,AG-18,AG 18,Epidermal growth factor receptor,RG50810,Tyrphostin A 23,Tyrphostin A-23,ErbB-1,Tyrphostin-23 118409-57-7 C10H6N2O2 BioChemical Cell Biology Cell Signaling and Neuroscience Kinase/Phosphatase Biology Receptor Tyrosine Kinase Inhibitors Epidermal Growth Factor Receptor (EGFR) Intracellular Signaling Protein Kinase All Inhibitors Inhibitors Tyrosine Kinase Inhibitors