ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Tyrosine derivatives >TYRPHOSTIN A9
TYRPHOSTIN A9
- CAS No.
- 10537-47-0
- Chemical Name:
- TYRPHOSTIN A9
- Synonyms
- AG 17;CS-743;SF 6847;gcp5126;s-15126;RG 50872;ent27910;MALONABEN;MALONOBEN;Malonobene
- CBNumber:
- CB2245711
- Molecular Formula:
- C18H22N2O
- Molecular Weight:
- 282.38
- MOL File:
- 10537-47-0.mol
- Modify Date:
- 2023/6/8 17:06:34
| Melting point | 141-143℃ (ethanol ) |
|---|---|
| Boiling point | 424.99°C (rough estimate) |
| Density | 1.0741 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | ethanol: 20 mg/mL |
| form | solid |
| pka | 7.55±0.40(Predicted) |
| color | yellow |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| CAS DataBase Reference | 10537-47-0(CAS DataBase Reference) |
| EPA Substance Registry System | Malonoben (10537-47-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P310-P302+P352+P312-P361+P364 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/24/25 | |||||||||
| Safety Statements | 36/37/39-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | OO3737000 | |||||||||
| HS Code | 2926.90.5050 | |||||||||
| HazardClass | 6.1 | |||||||||
| NFPA 704 |
|
TYRPHOSTIN A9 price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T182 | Tyrphostin A9 solid | 10537-47-0 | 5MG | ₹10868.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T182 | Tyrphostin A9 solid | 10537-47-0 | 25MG | ₹21346.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 658425 | AG 17 - CAS 10537-47-0 - Calbiochem Anti-proliferative agent that acts as a selective inhibitor of the platelet-derived growth factor receptor tyrosine kinase (IC?? = 500 nM). | 10537-47-0 | 5MG | ₹7070 | 2022-06-14 | Buy |
| TCI Chemicals (India) | T3667 | Tyrphostin A9 min. 98.0 % | 10537-47-0 | 25MG | ₹4800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | T3667 | Tyrphostin A9 min. 98.0 % | 10537-47-0 | 100MG | ₹16700 | 2022-05-26 | Buy |
TYRPHOSTIN A9 Chemical Properties,Uses,Production
Uses
Tyrphostin A9 can be used for inhibiting tyrosine kinase functions in C2C12 cells. It has also been used to disrupt membrane potential in mammalian cells.
General Description
A selective, cell-permeable, reversible, and substrate competitive inhibitor of the platelet-derived growth factor receptor tyrosine kinase (IC50 = 500 nM). Anti-proliferative agent. Uncoupler of oxidative phosphorylation. Induces apoptosis in vitro and cell growth arrest in NHL cell lines.
Biological Activity
Potent uncoupler of oxidative phosphorylation.
TYRPHOSTIN A9 Preparation Products And Raw materials
Global( 133)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | CHINA | 21149 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 23499 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
10537-47-0(TYRPHOSTIN A9)Related Search:
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ALPHA-CYANO-(3,5-DI-T-BUTYL-4-HYDROXY)CINNAMONITRILE
TYRPHOSTIN A9 \ SELECTIVE PDGF TYROSINE
TYRPHOSTIN A9 99+%
Malonobene
2-(3,5-di-tert-butyl-4-hydroxybenzylidene)Malononitrile
Tyrphostin 9 (SF 6847)
Propanedinitrile, 2-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-
[[3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXYPHENYL]METHYLENE]-PROPANEDINITRILE
3,5-DI-T-BUTYL-4-HYDROXY-BENZYLIDENEMALONONITRILE
3,5-DI-TERT-BUTYL-4-HYDROXYBENZYLIDENEMALONONITRILE
AG 17
2-[(3,5-DITERT-BUTYL-4-HYDROXYPHENYL)METHYLIDENE]PROPANEDINITRILE
2,6-Di-tert-butyl-4-(2,2-dicyanovinyl)phenol
3,5-di-tert-Butyl-4-hydroxybenzylidenemalonitrile
Tyrphostin 9/AG9
TYRPHOSTIN 9;NSC 242557; RG-50872;AG 17; GCP 5126
Tyrphostin 9 (RG-50872, Malonaben, SF 6847)
NSC 242557
SF 6847
RARECHEM AL BX 0198
RG 50872
((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-propanedinitril
2-((3,5-bis(1,1-dimethyl)-4-hydroxyphenyl)methylene)propanedinitrile
3,5-di-tert-butyl-4-hydroxybenzylidene-malononitril
ent27910
gcp5126
gulfs-15126
s-15126
TYRPHOSTIN 9
TYRPHOSTIN A9
TYRPHOSTIN AG 17
TYRPHOSTIN RG 50872
CHEMBRDG-BB 5272363
MALONABEN
MALONOBEN
Tyrphostin A9 (AG 17)
AG 17 - CAS 10537-47-0 - Calbiochem
Tyrphostin 9(AG-17)
TYRPHOSTIN 9;MALONOBEN;TYRPHOSTIN AG-17;SF 6847;GCP 5126;RG-50872;NSC 242557
CS-743
Tyrphostin9, >98%
TYRPHOSTIN A9OLECARBOXYLATE
Tyrphostin 9 (SF 6847, RG-50872)
[4-Hydroxy-3,5-bis(2-methyl-2-propanyl)benzylidene]malononitrile
TYRPHOSTIN A9 USP/EP/BP
Malonoben Tyrphostin 9
10537-47-0
Inhibitor of calcium release-activated calcium (CRAC) channels (see Dennis et al)
Cell Signaling and Neuroscience
BioChemical
Cell Biology
Kinase/Phosphatase Biology
Receptor Tyrosine Kinase Inhibitors
Platelet Derived Growth Factor Receptor (PDGFR)
Inhibitors