TYRPHOSTIN B48
- CAS No.
- 133550-35-3
- Chemical Name:
- TYRPHOSTIN B48
- Synonyms
- 494;AG 494;CS-2755;TYRPHOSTIN B48;-494 Tyrphostin;TYRPHOSTIN AG 494;AG-494 Tyrphostin;TyrphostinAG494>AG-494;AG 494;AG494;AG 494 (Tyrphostin AG 494)
- CBNumber:
- CB9319132
- Molecular Formula:
- C16H12N2O3
- Molecular Weight:
- 280.28
- MOL File:
- 133550-35-3.mol
- Modify Date:
- 2023/6/8 17:06:35
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P310+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P405-P501 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| RIDADR | 3439 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2926.90.4801 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
TYRPHOSTIN B48 price More Price(2)
TYRPHOSTIN B48 Chemical Properties,Uses,Production
Description
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative, compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-
Biological Activity
Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.7 μ M). Selective over ErbB2, PDGFR and insulin receptor kinase (IC 50 values are 42, 6 and > 100 μ M respectively).
TYRPHOSTIN B48 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 111)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | China | 694 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48467 | 58 | Inquiry |
| Chunchuang (Wuhan) Technology Co., Ltd | 15342225168 | China | 10005 | 58 | Inquiry |
133550-35-3(TYRPHOSTIN B48)Related Search:
(E)-2-CYANO-3-(3,4-DIHYDROXYPHENYL)-N-PHENYL-2-PROPENAMIDE
ALPHA-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMIDE
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(E)-2-Cyano-3-(3,4-dihydrophenyl)-N-phenyl-2-propenamide
(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-phenylacrylamide
-2-Cyano-3-(3,4-dihydroxyphenyl)
AG-494;AG 494;AG494
CS-2755
TyrphostinAG494>
2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-, (2E)-
494
-494 Tyrphostin
AG-494 Tyrphostin
DNA,ErbB-1,differentiation,Epidermal growth factor receptor,Cyclin dependent kinase,EGFR,HER1,Inhibitor,CDK,autophosphorylation,osteogenic,synthesis,Tyrphostin AG494,Tyrphostin AG 494,AG-494,activation,inhibit,Cdk2,AG494
133550-35-3
Cell Biology
Cell Signaling and Neuroscience
BioChemical
Receptor Tyrosine Kinase Inhibitors
Kinase/Phosphatase Biology
Epidermal Growth Factor Receptor (EGFR)
Protein Kinase
API
Intracellular Signaling