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ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Tyrosine derivatives >AG 1295

AG 1295

AG 1295 Structure
CAS No.
71897-07-9
Chemical Name:
AG 1295
Synonyms
AG 1295;NSC 380341;AG 1295 USP/EP/BP;TYRPHOSTIN AG 1295;TYROPHOSTIN AG1295;AG-1295 (NSC 380341;AG 1295, 10 mM in DMSO;TYRPHOSTIN AG 1295, 99+%;AG 1295 PLATELET-DERIVED GROW;6,7-DIMETHYL-2-PHENYLQUINOXALINE
CBNumber:
CB5683675
Molecular Formula:
C16H14N2
Molecular Weight:
234.3
MOL File:
71897-07-9.mol
MSDS File:
SDS
Modify Date:
2025/7/31 22:42:24
Request For Quotation

AG 1295 Properties

Melting point 121 °C
Boiling point 398.3±37.0 °C(Predicted)
Density 1.127±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form White solid
pka 1.29±0.30(Predicted)
color Yellow

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

AG 1295 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 658550 AG 1295 - CAS 71897-07-9 - Calbiochem A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC?? = 500 nM) and PD 71897-07-9 5MG ₹18910 2022-06-14 Buy
Product number Packaging Price Buy
658550 5MG ₹18910 Buy

AG 1295 Chemical Properties,Uses,Production

Description

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the treatment of atherosclerosis, restenosis, pulmonary fibrosis, and gliomas. AG-1295 is a quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC50s range from 0.3-1 μM). It inhibits PDGF-stimulated DNA synthesis with an IC50 value of 2.5 μM without affecting activity of the EGF receptor.

Uses

AG-1295 is a protein tyrosine kinase inhibitor. Antiproliferative agent used in the treatment of atherosclerosis, pulmonary fibrosis, and gliomas.

AG 1295 Preparation Products And Raw materials

Raw materials

Preparation Products

AG 1295 Suppliers

Global( 94)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29855 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354; +17819995354 United States 32376 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 22418 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354; United States 38838 58 Inquiry
Aladdin Scientific United States 52924 58 Inquiry
DAYANG CHEM (HANGZHOU) CO.,LTD +86-88938639 +86-17705817739 China 53900 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39927 58 Inquiry
Guangzhou Weijia Technology Co., Ltd. 020-84224925 18300190102 CHINA 6757 58 Inquiry
Shanghai Yaoyun Biological Technology Co., Ltd. 400-002-6926 CHINA 6448 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
career henan chemical co 58
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
DAYANG CHEM (HANGZHOU) CO.,LTD 58
Chongqing Chemdad Co., Ltd 58
Guangzhou Weijia Technology Co., Ltd. 58
Shanghai Yaoyun Biological Technology Co., Ltd. 58

AG 1295 Spectrum

AG 1295(71897-07-9)1HNMR

71897-07-9(AG 1295)Related Search:

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6,7-DIMETHYL-2-PHENYLQUINOXALINE AG 1295 TYROPHOSTIN AG1295 TYRPHOSTIN AG 1295 AG 1295 PLATELET-DERIVED GROW TYRPHOSTIN AG 1295, 99+% Quinoxaline, 6,7-dimethyl-2-phenyl- AG-1295 (NSC 380341 NSC 380341 AG 1295 USP/EP/BP Platelet-derived growth factor receptor,RTK,AG 1295,inhibit,PDGF-receptor,AG-1295,autophosphorylation,Inhibitor,AG1295,PDGFR AG 1295, 10 mM in DMSO 71897-07-9 70897-07-9 Cell Signaling and Neuroscience Cell Biology BioChemical Kinase/Phosphatase Biology Receptor Tyrosine Kinase Inhibitors Platelet Derived Growth Factor Receptor (PDGFR)