AG 1295
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- ₹18910
- Product name: AG 1295
- CAS: 71897-07-9
- MF: C16H14N2
- MW: 234.3
- EINECS:
- MDL Number:MFCD00270912
- Synonyms:6,7-DIMETHYL-2-PHENYLQUINOXALINE;AG 1295;TYROPHOSTIN AG1295;TYRPHOSTIN AG 1295;AG 1295 PLATELET-DERIVED GROW;TYRPHOSTIN AG 1295, 99+%;Quinoxaline, 6,7-dimethyl-2-phenyl-;AG-1295 (NSC 380341
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product number658550
- Product descriptionAG 1295 - CAS 71897-07-9 - Calbiochem A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC?? = 500 nM) and PD
- Packaging5MG
- Price₹18910
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 658550 | AG 1295 - CAS 71897-07-9 - Calbiochem A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC?? = 500 nM) and PD | 5MG | ₹18910 | 2022-06-14 | Buy |
Properties
Melting point :121 °C
Boiling point :398.3±37.0 °C(Predicted)
Density :1.127±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :White solid
pka :1.29±0.30(Predicted)
color :Yellow
Boiling point :398.3±37.0 °C(Predicted)
Density :1.127±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :White solid
pka :1.29±0.30(Predicted)
color :Yellow
Safety Information
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Description
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the treatment of atherosclerosis, restenosis, pulmonary fibrosis, and gliomas. AG-1295 is a quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC50s range from 0.3-1 μM). It inhibits PDGF-stimulated DNA synthesis with an IC50 value of 2.5 μM without affecting activity of the EGF receptor.More related product prices
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