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(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE

(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Structure
  • ₹7500 - ₹26100
  • Product name: (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
  • CAS: 85416-75-7
  • MF: C16H21NO3
  • MW: 275.34
  • EINECS:
  • MDL Number:MFCD03093860
  • Synonyms:(4R)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE;(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE;(S)-(+)-ROLIPRAM;(R)-(-)-ROLIPRAM;(4R)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one;Rolipram (R)-(-)-;(4R)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(R)-(-)-Rolipram
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • TCI Chemicals (India)

Package

  • 10MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberR0182
  • Product description(R)-(-)-Rolipram
  • Packaging10MG
  • Price₹7500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0182
  • Product description(R)-(-)-Rolipram
  • Packaging50MG
  • Price₹26100
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) R0182 (R)-(-)-Rolipram 10MG ₹7500 2022-05-26 Buy
TCI Chemicals (India) R0182 (R)-(-)-Rolipram 50MG ₹26100 2022-05-26 Buy

Properties

Melting point :132.0 to 136.0 °C
Boiling point :472.7±45.0 °C(Predicted)
Density :1.155±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :16.02±0.40(Predicted)
form :White to off-white solid.
color :Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

R-(-)-Rolipram is the R-entantiomer of rolipram. This compound has been shown to strongly inhibit the catalytic activities of PDE4 (phosphodiesterase 4), which is selective for cAMP, an important secondary messenger molecule in signal transduction. Experiments have revealed that high-affinity binding sites require residues within the catalytic domains and residues flanking the N-/C-terminal to the catalytic region of amino acids. Other studies suggest that the deactivation of PDE4 has been reported to affect other cellular functions.

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Suppliers and manufacturers

Career Henan Chemica Co
(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
₹1.00 /1g
(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE CAS:85416-75-7
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