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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Peripheral vasodilators >Pentoxifylline

Pentoxifylline

Pentoxifylline Structure
  • ₹2400 - ₹7500
  • Product name: Pentoxifylline
  • CAS: 6493-05-6
  • MF: C13H18N4O3
  • MW: 278.31
  • EINECS:229-374-5
  • MDL Number:MFCD00063379
  • Synonyms:3,7-DIHYDRO-3,7-DIMETHYL-1-(5-OXOHEXYL)-1H-PURINE-2,6-DIONE;PENTOXIFYLLINE;PENTOXYIFYLLINE;PENTOXYPHYLINE;1-(5-Oxohexyl)-3,7-dimethylxanthine;bl191 ;Dimethyloxohexylxanthine;Durapental
Price2 Properties Safety Information Description
2 prices
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Brand

  • TCI Chemicals (India)

Package

  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberP2050
  • Product descriptionPentoxifylline
  • Packaging5G
  • Price₹2400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP2050
  • Product descriptionPentoxifylline
  • Packaging25G
  • Price₹7500
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P2050 Pentoxifylline 5G ₹2400 2022-05-26 Buy
TCI Chemicals (India) P2050 Pentoxifylline 25G ₹7500 2022-05-26 Buy

Properties

Melting point :98-100°C
Boiling point :421.13°C (rough estimate)
Density :1.1713 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :H2O: ≥43 mg/mL
form :solid
pka :0.50±0.70(Predicted)
color :white
λmax :276nm(lit.)
Merck :14,7136
CAS DataBase Reference :6493-05-6(CAS DataBase Reference)
NIST Chemistry Reference :Pentoxifylline(6493-05-6)
EPA Substance Registry System :1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)- (6493-05-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Description

Pentoxifylline is a methylxanthine derivative. It has been shown to have anti-inflammatory activity, inhibiting LPS-induced TNF-α production in isolated peripheral blood mononuclear cells (IC50 = 85 μM) and suppressing LPS-induced leukopenia in mice. Pentoxifylline weakly inhibits the generation of phosphatidic acid (IC50 = 500 μM) from LPS-activated lysophosphatidic acyl transferase (LPAAT), and weakly antagonizes A1 and A2 adenosine receptors. It also inhibits human acidic mammalian chitinase, human chitotriosidase, and chitinase B1 from Aspergillus fumigatus (IC50s = 49, 98, and 126 μM, respectively).

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