EHNA HYDROCHLORIDE
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- ₹10670
- Product name: EHNA HYDROCHLORIDE
- CAS: 51350-19-7
- MF: C14H23N5O
- MW: 277.37
- EINECS:
- MDL Number:MFCD00151066
- Synonyms:9-ERYTHRO-(2-HYDROXY-3-N-NONYL) ADENINE HYDROCHLORIDE;ERYTHRO-9-(2-HYDROXY-3-NONYL)ADENINE, HCL;ERYTHRO-9-(2-HYDROXY-3-NONYL)ADENINE HYDROCHLORIDE;ERYTHRO-9-AMINO-BETA-HEXYL-ALPHA-METHYL-9H-PURINE-9-ETHANOL HYDROCHLORIDE;EHNA;EHNA HCL;EHNA HYDROCHLORIDE;MEP1 HYDROCHLORIDE
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Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- ManufacturerSigma-Aldrich(India)
- Product number324630
- Product descriptionEHNA, Hydrochloride - CAS 51350-19-7 - Calbiochem The racemic mixture of a cell-permeable adenine derivative that acts as a PDE II-selective phosphodiesterase inhibitor and adenosine deaminase.
- Packaging10MG
- Price₹10670
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 324630 | EHNA, Hydrochloride - CAS 51350-19-7 - Calbiochem The racemic mixture of a cell-permeable adenine derivative that acts as a PDE II-selective phosphodiesterase inhibitor and adenosine deaminase. | 10MG | ₹10670 | 2022-06-14 | Buy |
Properties
Melting point :183～184℃
storage temp. :0-6°C
solubility :DMSO: 12 mg/mL
form :solid
color :white
Stability :Stable for 2 years as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :51350-19-7
storage temp. :0-6°C
solubility :DMSO: 12 mg/mL
form :solid
color :white
Stability :Stable for 2 years as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :51350-19-7
Safety Information
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Description
EHNA (51350-19-7) inhibits phosphodiesterase 2 (PDE2) (IC50 = 0.8 – 5.5 μM in a variety of tissues and species) over PDE1, PDE3, or PDE4 (IC50 values > 100 μM).1,2 It also inhibits adenosine deaminase (ADA), IC50 = 1.2 and 1.5 μM in human RBCs and astrocytoma cells, respectively3, which may be responsible for its ability to induce apoptosis in malignant pleural mesothelioma cell lines4. Because it blocks breakdown of adenosine to inosine and hypoxanthine, EHNA prevents formation of free radical substrates, protecting against cardiac reperfusion-mediated injury.5 It inhibits differentiation and maintains expression of pluripotency markers in hESCs, but not through inhibition of PDEs or ADA.6Related product price
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