BRL 50481
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- ₹9600 - ₹68338.23
- Product name: BRL 50481
- CAS: 433695-36-4
- MF: C9H12N2O4S
- MW: 244.27
- EINECS:1592732-453-0
- MDL Number:MFCD03039912
- Synonyms:5-NITRO-2,N,N-TRIMETHYLBENZENESULFONAMIDE;BRL 50481;N,N,2-TRIMETHYL-5-NITRO-BENZENESULFONAMIDE;3-(N,N-Dimethylsulfonamido)-4-methylnitrobenzene,5-Nitro-2-N,N-trimethylbenzenesulfonamide;Benzenesulfonamide, N,N,2-trimethyl-5-nitro-;-50481
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 200MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberT3112
- Product descriptionN,N,2-Trimethyl-5-nitrobenzenesulfonamide
- Packaging200MG
- Price₹9600
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberT3112
- Product descriptionN,N,2-Trimethyl-5-nitrobenzenesulfonamide
- Packaging1G
- Price₹14500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberB0936
- Product descriptionBRL 50481 ≥98% (HPLC), solid
- Packaging5MG
- Price₹17060.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberB0936
- Product descriptionBRL 50481 ≥98% (HPLC), solid
- Packaging25MG
- Price₹68338.23
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | T3112 | N,N,2-Trimethyl-5-nitrobenzenesulfonamide | 200MG | ₹9600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | T3112 | N,N,2-Trimethyl-5-nitrobenzenesulfonamide | 1G | ₹14500 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | B0936 | BRL 50481 ≥98% (HPLC), solid | 5MG | ₹17060.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B0936 | BRL 50481 ≥98% (HPLC), solid | 25MG | ₹68338.23 | 2022-06-14 | Buy |
Properties
Melting point :65-67°C
Boiling point :391.1±52.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 12 mg/mL
form :solid
pka :-5?+-.0.70(Predicted)
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :391.1±52.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 12 mg/mL
form :solid
pka :-5?+-.0.70(Predicted)
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Description
BRL 50481 is a potent, selective inhibitor of phosphodiesterase (PDE) 7, inhibiting human recombinant PDE7A1 with a Ki value of 180 nM. It is much less effective against PDE3 and PDE4 and is without effect against PDE1B, PDE1C, PDE2, and PDE5. Through its effects on PDE7A1, BRL 50481 enhances the inhibitory effects of the PDE4 blocker rolipram on monocytes, lung macrophages, and CD8+ T-lymphocytes. BRL 50481, at 30 μM, promotes apoptosis in chronic lymphocytic leukemia cells overexpressing PDE7B, suggesting that this compound also acts against PDE7B. BRL 50481 can be used to evaluate the role of PDE7 isoforms in intracellular signaling.More related product prices
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Suppliers and manufacturers
A.J Chemicals
TCI Chemicals (India) Pvt. Ltd.
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
InvivoChem
Hefei TNJ Chemical Industry Co.,Ltd.
LEAP CHEM CO., LTD.
Hebei Guanlang Biotechnology Co., Ltd.
