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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Tyrosine derivatives >AG 18

AG 18

AG 18 Structure
  • ₹6691 - ₹49091.38
  • Product name: AG 18
  • CAS: 118409-57-7
  • MF: C10H6N2O2
  • MW: 186.17
  • EINECS:
  • MDL Number:MFCD00133899
  • Synonyms:RARECHEM AL BX 0069;RG-50810;TYRPHOSTIN RG 50858;TYRPHOSTIN AG 18;TYRPHOSTIN A23;TYRPHOSTIN 23;ALPHA-CYANO-(3,4-DIHYDROXY)CINNAMONITRILE;AG 18
Price8 Properties Safety Information Description
8 prices
Selected condition：

Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5mg
  • 10mg
  • 25mg
  • 100MG
  • ManufacturerALFA India
  • Product numberALF-J60308-LB0
  • Product descriptionTyrphostin A23, 99%
  • Packaging5mg
  • Price₹6691
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J60308-MA
  • Product descriptionTyrphostin A23, 99%
  • Packaging10mg
  • Price₹21386
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J60308-MB
  • Product descriptionTyrphostin A23, 99%
  • Packaging25mg
  • Price₹29743
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT3503
  • Product descriptionTyrphostin A23 min. 98.0 %
  • Packaging25MG
  • Price₹8800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT3503
  • Product descriptionTyrphostin A23 min. 98.0 %
  • Packaging100MG
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number658395
  • Product descriptionAG 18 - CAS 118409-57-7 - Calbiochem A broad-spectrum protein tyrosine kinase inhibitor.
  • Packaging5MG
  • Price₹9490
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7165
  • Product descriptionTyrphostin 23 ≥98%
  • Packaging5MG
  • Price₹12676.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7165
  • Product descriptionTyrphostin 23 ≥98%
  • Packaging25MG
  • Price₹49091.38
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J60308-LB0 Tyrphostin A23, 99% 5mg ₹6691 2022-05-26 Buy
ALFA India ALF-J60308-MA Tyrphostin A23, 99% 10mg ₹21386 2022-05-26 Buy
ALFA India ALF-J60308-MB Tyrphostin A23, 99% 25mg ₹29743 2022-05-26 Buy
TCI Chemicals (India) T3503 Tyrphostin A23 min. 98.0 % 25MG ₹8800 2022-05-26 Buy
TCI Chemicals (India) T3503 Tyrphostin A23 min. 98.0 % 100MG ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) 658395 AG 18 - CAS 118409-57-7 - Calbiochem A broad-spectrum protein tyrosine kinase inhibitor. 5MG ₹9490 2022-06-14 Buy
Sigma-Aldrich(India) T7165 Tyrphostin 23 ≥98% 5MG ₹12676.08 2022-06-14 Buy
Sigma-Aldrich(India) T7165 Tyrphostin 23 ≥98% 25MG ₹49091.38 2022-06-14 Buy

Properties

Melting point :225°C
Boiling point :421.1±45.0 °C(Predicted)
Density :1.428±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO, ethanol, or DMF
pka :7.26±0.18(Predicted)
form :Yellow solid
color :Yellow
λmax :464nm(DMSO)(lit.)
Stability :Store in refrigerator

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.

Description

Tyrphostin inhibit protein tyrosine kinase and block the EGF-dependent autophosphorylation of the receptor. The inhibitors can bind to the EGF receptor kinase domain with different affinities. It also inhibits PDGFR kinase. Tyrphostin A23 has been used to inhibit agonist-induced GP IIb- IIIa activation in permeabilized platelets and in other studies to block calcium channel currents in vascular smooth muscle cells. . Tyrphostin A23 can also inhibit the internalization of (125)I-transferrin in Heb7a cells.

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