RO 20-1724

CAS No.: 29925-17-5

Chemical Name:: RO 20-1724

Synonyms: RO 20-1724;ro 20-172;R 020-1724;Ro-20-1724 - CAS 29925-17-5 - Calbiochem;4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDONE;4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE;4-(3-BUTOXY-4-METHOXY-BENZYL)IMIDAZOLIDIN-2-ONE;RO 20-1724, Phosphodiesterase 4 (PDE4) inhibitor;4-(3-BUTOXY-4-METHOXYPHENYL)METHYL-2-IMIDAZOLIDONE;4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one solid

CBNumber:: CB0710844

Molecular Formula:: C15H22N2O3

Molecular Weight:: 278.35

MOL File:: 29925-17-5.mol

MSDS File:: SDS

Modify Date:: 2025/1/27 9:38:02

Request For Quotation

RO 20-1724 Properties

Boiling point	483.8±25.0 °C(Predicted)
Density	1.099±0.06 g/cm3(Predicted)
storage temp.	room temp
solubility	ethanol: 7 mg/mL
form	solid
pka	14.54±0.40(Predicted)
color	White
biological source	synthetic (organic)
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.
CAS DataBase Reference	29925-17-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H335-H315-H319

Precautionary statements

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

NFPA 704

	0
2		0

RO 20-1724 price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	B8279	4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one solid	29925-17-5	100MG	₹10430	2022-06-14	Buy
Sigma-Aldrich(India)	B8279	4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one solid	29925-17-5	500MG	₹44210	2022-06-14	Buy
Sigma-Aldrich(India)	557502	Ro-20-1724 - CAS 29925-17-5 - Calbiochem A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC?? = 2 μM).	29925-17-5	100MG	₹11880.01	2022-06-14	Buy

Product number	Packaging	Price	Buy
B8279	100MG	₹10430	Buy
B8279	500MG	₹44210	Buy
557502	100MG	₹11880.01	Buy

RO 20-1724 Chemical Properties,Uses,Production

Uses

Ro 20-1724 is a cell-permeable, cAMP-specific phosphodiesterase type IV (PDE4) inhibitor (IC50 = 2 μM). It weakly inhibits PDE3 with a Ki value greater than 25 μM. Ro 20-1724 inhibits the release of cytokines and other inflammatory signals as well as prevents the development of reactive oxygen species. It is often used to study cAMP-related functions in vascular cells.

Biological Activity

Widely used inhibitor of cyclic nucleotide phosphodiesterase, selective for PDE4 (IC 50 = 2.0 μ M). Also available as part of the Phosphodiesterase Inhibitor Tocriset™ .

Biochem/physiol Actions

Inhibitor of cAMP phosphodiesterase. IC50 33 μM in vascular smooth muscle of the aorta.

RO 20-1724 Preparation Products And Raw materials

Raw materials

Preparation Products

RO 20-1724 Suppliers

Global( 114)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32159	58	Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	China	49734	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8467	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43340	58	Inquiry
Aladdin Scientific		United States	57505	58	Inquiry
DAYANG CHEM (HANGZHOU) CO.,LTD	+8617705817739	China	53881	58	Inquiry
Merck Millipore	1-400-889-1988 400-889-1988	China	59839	58	Inquiry
Shanghai Maclean Biochemical Technology Co., LTD	021-50706066 15221275939	China	29784	58	Inquiry
Biosynth Biological Technology (Suzhou) Co Ltd	51288865780	China	233051	58	Inquiry
JiangSu Star Science Co.,Ltd	400-400-605-7200-7200 15335295587	China	3761	58	Inquiry

Supplier	Advantage
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Merck Millipore	58
Shanghai Maclean Biochemical Technology Co., LTD	58
Biosynth Biological Technology (Suzhou) Co Ltd	58
JiangSu Star Science Co.,Ltd	58

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RO 20-1724 2-Imidazolidinone, 4-((3-(cyclopentyloxy)-4-methoxyphenyl)methyl)- AKOS BB-3072

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4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE 4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDONE 4-(3-BUTOXY-4-METHOXY-BENZYL)IMIDAZOLIDIN-2-ONE 4-[(3-BUTOXY-4-METHOXYPHENYL)METHYL]-2-IMIDAZOLIDINONE 4-(3-BUTOXY-4-METHOXYPHENYL)METHYL-2-IMIDAZOLIDONE ro 20-172 RO 20-1724 4-[(3-Butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one Ro-20-1724 - CAS 29925-17-5 - Calbiochem 2-Imidazolidinone, 4-[(3-butoxy-4-methoxyphenyl)methyl]- 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one solid R 020-1724 neuroprotective,Ro 201724,Ro 20-174,Ro 20 1724,Ro 20-1724,phosphodiesterase,cognitive,cAMP,antioxidant,inhibit,Inhibitor,Phosphodiesterase (PDE) RO 20-1724, Phosphodiesterase 4 (PDE4) inhibitor 29925-17-5 Inhibitor of cAMP phosphodiesterase. IC50 33 uM in vascular smooth muscle of the aorta. Cell Signaling and Neuroscience Cell Biology BioChemical Phosphodiesterase Inhibitors G Proteins and Cyclic Nucleotides Cyclic Nucleotide Metabolism Cyclic Nucleotide related A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase.