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RO 20-1724

RO 20-1724 Structure
  • ₹10430 - ₹44210
  • Product name: RO 20-1724
  • CAS: 29925-17-5
  • MF: C15H22N2O3
  • MW: 278.35
  • EINECS:
  • MDL Number:MFCD00077397
  • Synonyms:4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE;4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDONE;4-(3-BUTOXY-4-METHOXY-BENZYL)IMIDAZOLIDIN-2-ONE;4-[(3-BUTOXY-4-METHOXYPHENYL)METHYL]-2-IMIDAZOLIDINONE;4-(3-BUTOXY-4-METHOXYPHENYL)METHYL-2-IMIDAZOLIDONE;ro 20-172;RO 20-1724;4-[(3-Butoxy-4-methoxyphenyl)methyl]imidazolidin-2-one
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberB8279
  • Product description4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one solid
  • Packaging500MG
  • Price₹44210
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number557502
  • Product descriptionRo-20-1724 - CAS 29925-17-5 - Calbiochem A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC?? = 2 μM).
  • Packaging100MG
  • Price₹11880.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB8279
  • Product description4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one solid
  • Packaging100MG
  • Price₹10430
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) B8279 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one solid 500MG ₹44210 2022-06-14 Buy
Sigma-Aldrich(India) 557502 Ro-20-1724 - CAS 29925-17-5 - Calbiochem A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC?? = 2 μM). 100MG ₹11880.01 2022-06-14 Buy
Sigma-Aldrich(India) B8279 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one solid 100MG ₹10430 2022-06-14 Buy

Properties

Boiling point :483.8±25.0 °C(Predicted)
Density :1.099±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :ethanol: 7 mg/mL
form :solid
pka :14.54±0.40(Predicted)
color :White
biological source :synthetic (organic)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.
CAS DataBase Reference :29925-17-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Ro 20-1724 is a cell-permeable, cAMP-specific phosphodiesterase type IV (PDE4) inhibitor (IC50 = 2 μM). It weakly inhibits PDE3 with a Ki value greater than 25 μM. Ro 20-1724 inhibits the release of cytokines and other inflammatory signals as well as prevents the development of reactive oxygen species. It is often used to study cAMP-related functions in vascular cells.

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