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NS-398

NS-398 구조식 이미지

카스 번호:: 123653-11-2

상품명:: NS-398

동의어(영문):: NS NS;NS-398;CS-2231;NS-398 98%;Taisho NS 398;NS-398 (NS 398;NS-398 USP/EP/BP;glycolysis inhibitor;NS 398, COX-2 inhibitor;mitochondrial complex I inhibitor

CBNumber:: CB1754593

분자식:: C13H18N2O5S

포뮬러 무게:: 314.36

MOL 파일:: 123653-11-2.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 153

NS-398 속성

녹는점: 124-126 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))

끓는 점: 490.6±55.0 °C(Predicted)

밀도: 1.377±0.06 g/cm3(Predicted)

RTECS 번호: PB0473500

저장 조건: Sealed in dry,Room Temperature

용해도: DMSO: >5mg/mL

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 6.33±0.10(Predicted)

색상: 회백색

안전

안전지침서	22-24/25
WGK 독일	3
HS 번호	2935.90.9500

NS-398 C화학적 특성, 용도, 생산

개요

NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC₅₀ values for human recombinant COX-1 and -2 are 75 and 1.77 μM, respectively. The IC₅₀ values for ovine COX-1 and -2 are 220 and 0.15 μM, respectively.

용도

NS-398 is a selective Cox-2 inhibitor neuroprotective agent.

정의

ChEBI: A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

생물학적 활성

Selective cyclooxygenase-2 inhibitor (IC 50 values are 3.8 and > 100 μ M for COX-2 and COX-1 respectively). Induces apoptosis in colorectal tumor cells and elevates COX-2 protein expression in vitro . Orally active and non-ulcerogenic analgesic and anti-inflammatory in vivo .

NS-398 준비 용품 및 원자재

원자재

준비 용품

글리옥살 아크릴아마이드

NS-398 공급 업체

글로벌( 153)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12834	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5857	58
Hebei Weibang Biotechnology Co., Ltd	+8617732866630	bess@weibangbio.com	China	18151	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	970	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32956	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30238	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22787	58
Henan Alfa Chemical Co., Ltd			China	11415	58

NS-398 관련 검색:

칼륨 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-헵타데카플루오로-1- 옥탄술폰산 펜타나트륨 펜텐산 CALPHOSTIN C Trypsin inhibitor AG 18 AG 490 TYRPHOSTIN A25 Roscovitine Potassium clavulanate Ancymidol NS-398 3-ISOPROPOXYANILINE 4-NITRO METHANESULFONANILIDE 4-nitro-o-phenetidine N-(2-METHOXY-4-NITRO-PHENYL)-METHANESULFONAMIDE 4-NITRO-2-PROPOXY-PHENYLAMINE NS-398 (N-(2-Cyclohexyloxy-4-nitrophenyl) -Methanesulfonamide) Methanesulfonamide, N-(2-ethoxyphenyl)- (9CI)