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4'-Hydroxy-3'-methylacetophenone

4'-Hydroxy-3'-methylacetophenone Structure
CAS No.
876-02-8
Chemical Name:
4'-Hydroxy-3'-methylacetophenone
Synonyms
4-HYDROXY-3-METHYLACETOPHENONE;4'-Hydroxy-3'-methyl;4-ACETYL-2-METHYLPHENOL;TrichIoroacetyI chIorine;4'-HYDROXY-3'-METHYLACETOPHENONE;4'-Hydroxy-3'-methylacetophenone;3'-Methyl-4'-Hydroxy Acetophenone;4'-Hydroxy-3'-methylacetophenone>1-(4-HYDROXY-3-METHYLPHENYL)ETHANONE;4’-Hydroxy-3’-Methyl acetophenone99%
CBNumber:
CB7468317
Molecular Formula:
C9H10O2
Molecular Weight:
150.17
MOL File:
876-02-8.mol
MSDS File:
SDS
Modify Date:
2023/5/25 18:01:18

4'-Hydroxy-3'-methylacetophenone Properties

Melting point 107-109 °C(lit.)
Boiling point 175°C 1mm
Density 1.0858 (rough estimate)
refractive index 1.5180 (estimate)
Flash point 175°C/1mm
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka 8.52±0.18(Predicted)
form Solid
color Off-White to Pale Beige
BRN 2041839
Stability Hygroscopic
LogP 1.395 (est)
CAS DataBase Reference 876-02-8(CAS DataBase Reference)
NIST Chemistry Reference 4-Hydroxy-3-methylacetophenone(876-02-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  36/37/39-26-22-37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29143990
NFPA 704
1
2 0

4'-Hydroxy-3'-methylacetophenone price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) H38004 4′-Hydroxy-3′-methylacetophenone 97% 876-02-8 5G ₹5022.8 2022-06-14 Buy
Sigma-Aldrich(India) H38004 4′-Hydroxy-3′-methylacetophenone 97% 876-02-8 25G ₹34022.98 2022-06-14 Buy
ALFA India ALF-A18540-14 4'-Hydroxy-3'-methylacetophenone, 98% 876-02-8 25g ₹16035 2022-05-26 Buy
TCI Chemicals (India) H0791 4'-Hydroxy-3'-methylacetophenone min. 98.0 % 876-02-8 5G ₹4000 2022-05-26 Buy
ALFA India ALF-A18540-06 4'-Hydroxy-3'-methylacetophenone, 98% 876-02-8 5g ₹5448 2022-05-26 Buy
Product number Packaging Price Buy
H38004 5G ₹5022.8 Buy
H38004 25G ₹34022.98 Buy
ALF-A18540-14 25g ₹16035 Buy
H0791 5G ₹4000 Buy
ALF-A18540-06 5g ₹5448 Buy

4'-Hydroxy-3'-methylacetophenone Chemical Properties,Uses,Production

Chemical Properties

white to light beige crystalline powder or

Uses

4''-Hydroxy-3''-methylacetophenone is used in the synthesis of 3-De(hydroxymethyl)-3-methyl Salmeterol (D230650), which is an impurity of β2-Adrenergic agonist Salmeterol (S090100).

Preparation

Preparation by dealkylation of 4-hydroxy-5-methyl-2-iso-propylacetophenone with aluminium chloride in chloro-benzene at 50° (53%).

4'-Hydroxy-3'-methylacetophenone Preparation Products And Raw materials

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Ethanone, 1-(4-hydroxy-3-methylphenyl)- 1-(4-HYDROXY-3-METHYLPHENYL)ETHAN-1-ONE 1-(4-HYDROXY-3-METHYLPHENYL)ETHANONE 4-ACETYL-2-METHYLPHENOL 4'-HYDROXY-3'-METHYLACETOPHENONE 3'-Methyl-4'-Hydroxy Acetophenone 4'-Hydroxy-3'-methylacetophenone, 99.5+% 4'-Hydroxy-3'-methyl 4-hydroxy-3-methylphenyl methyl ketone TrichIoroacetyI chIorine 4'-Hydroxy-3'-methylacetophenone> 4’-Hydroxy-3’-Methyl acetophenone99% 4-HYDROXY-3-METHYLACETOPHENONE 4'-Hydroxy-3'-methylacetophenone 876-02-8 976-02-8 HOC6H3CH3COCH3 KETONE Organic Building Blocks Ketones C9 Carbonyl Compounds Building Blocks Chemical Synthesis Organic Building Blocks Aromatic Acetophenones & Derivatives (substituted) Benzene series Benzene derivatives C9 Carbonyl Compounds Ketones Building Blocks Carbonyl Compounds