HYDROXYZINE HYDROCHLORIDE
![HYDROXYZINE HYDROCHLORIDE Structure](StructureFile/ChemBookStructure1/GIF/CB7484355.gif)
- CAS No.
- Chemical Name:
- HYDROXYZINE HYDROCHLORIDE
- Synonyms
- HYDROXYZINE HYDROCHLORIDE
- CBNumber:
- CB7484355
- Molecular Formula:
- C21H28Cl2N2O2
- Molecular Weight:
- 411.37
- MOL File:
- Mol file
HYDROXYZINE HYDROCHLORIDE Chemical Properties,Uses,Production
Originator
Atarax,UCB,France,1956
Manufacturing Process
A mixture of 0.1 mol of N-mono-1-p-chlorobenzohydrylpiperazine and 0.1 mol
of 1-chloro-2-(2-hydroxy-ethoxy)-ethane is heated for 3 hours to 150°C. The
mass is then taken up in 100 ml of benzene and 100 ml of a 10% aqueous
solution of NaOH; decanting takes place, and the benzene solution is washed
with water and the solvent is evaporated. Vacuum distilling of the residue
yields 1-p-chlorobenzohydryl-4-[2-(2-hydroxy-ethoxy)-ethyl]-piperazine, BP
220°C/0.5 mm Hg.
The corresponding dihydrochloride is prepared by dissolving this base in about
twice its weight of alcohol, by treating it with excess of gaseous HCl and by
precipitating it with ether. The solvent is decanted and the residue, dissolved
in a minimum of alcohol, crystallizes on the addition of ether, MP 193°C.
Therapeutic Function
Tranquilizer
HYDROXYZINE HYDROCHLORIDE Preparation Products And Raw materials
HYDROXYZINE HYDROCHLORIDE Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
HEMA PHARMACEUTICALS PVT LTD | +91-9537936912 +91-9537936912 | Gujarat, India | 48 | 58 | Inquiry |
Hema Pharmaceuticals Pvt. Ltd. | 08048250474Ext 875 | Gujarat, India | 24 | 58 | Inquiry |
MANGALAM DRUGS AND ORGANICS LIMITED | 08147509329 | Uttar Pradesh, India | 50 | 58 | Inquiry |
SRIKEM LABORATORIES PVT LTD | +91-2224055088 | New Delhi, India | 5 | 58 | Inquiry |
KREATIVE ORGANICS PRIVATE LIMITED | +91 40 2355 3624 | New Delhi, India | 8 | 58 | Inquiry |
IPCA Laboratories Limited | +91 (22) 6210 5000 | New Delhi, India | 56 | 58 | Inquiry |
SYMED LABS LIMITED | New Delhi, India | 6 | 58 | Inquiry | |
CALYX CHEMICALS AND PHARMACEUTICALS LTD | +91 7738383880 | New Delhi, India | 32 | 58 | Inquiry |
IPCA LABORATORIES LTD | +91 (22) 6210 5000 | New Delhi, India | 43 | 58 | Inquiry |
SYMED LABS LTD | +91 40 23635000 to+91 40 23635010 | New Delhi, India | 16 | 58 | Inquiry |