9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID

9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID Structure
CAS No.
24769-56-0
Chemical Name:
9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID
Synonyms
TETRANOR-PGEM;Tetranor-PGEM-13C6;prostaglandin E2-UM;TETRANOR PROSTAGLANDIN E METABOLITE;tetranor-PGEM Lipid Maps MS Standard;9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID;11alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoicacid;Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-ε,3-dioxo-, (1R,2R,5R)-
CBNumber:
CB7492637
Molecular Formula:
C16H24O7
Molecular Weight:
328.36
MOL File:
24769-56-0.mol
Modify Date:
2024/7/2 8:55:17

9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID Properties

Boiling point 622.2±50.0 °C(Predicted)
Density 1.266±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: Not Stable; PBS (pH 7.2): 1 mg/ml
form Liquid
pka 4.61±0.10(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID Chemical Properties,Uses,Production

Description

tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis. About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy males excrete 7-40 μg of tetranor-PGEM over a 24-hour period.

Uses

The major urinary metabolite of Prostaglandin E2 (P838610).

Definition

ChEBI: A prostanoid that is prostaglandin E2 in which the acyclic hydroxy group has been oxidised to the corresponding ketone, the methyl group has been oxidised to the corresponding carboxylic acid and the 6-carboxyhexenyl group has been oxidatively cleaved to a 2-carboxyethyl group. It is the major urinary metabolite of prostaglandin E2.

9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID Suppliers

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11alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoicacid 9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID TETRANOR PROSTAGLANDIN E METABOLITE TETRANOR-PGEM tetranor-PGEM Lipid Maps MS Standard prostaglandin E2-UM Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-ε,3-dioxo-, (1R,2R,5R)- Tetranor-PGEM-13C6 24769-56-0 Chiral Reagents Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals