CD437

CD437 Structure
CAS No.
125316-60-1
Chemical Name:
CD437
Synonyms
CS-2691;ADAP-IME;Ro472077;Ro 472077;Ro-472077;CD 437/AHPN;AHPN;CD 437;CD-437;CD437;CD-437;CD 437;Adapalene IMpurity F;O-DesMethyl Adapalene
CBNumber:
CB7503287
Molecular Formula:
C27H26O3
Molecular Weight:
398.49
MOL File:
125316-60-1.mol
MSDS File:
SDS
Modify Date:
2023/9/4 15:50:00

CD437 Properties

Melting point 271.6-276 °C
Boiling point 595.0±50.0 °C(Predicted)
Density 1.290
storage temp. -20°C
solubility DMSO: 26 mg/mL
form solid
pka 4.17±0.30(Predicted)
color yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501
Safety Statements  22-24/25
WGK Germany  3
RTECS  QJ1975900

CD437 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C5865 CD437 ≥98% (HPLC), solid 125316-60-1 5MG ₹20556.68 2022-06-14 Buy
Sigma-Aldrich(India) C5865 CD437 ≥98% (HPLC), solid 125316-60-1 25MG ₹81934.43 2022-06-14 Buy
Sigma-Aldrich(India) 178496 Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem The Apoptosis Activator VI, CD437/AHPN, also referenced under CAS 125316-60-1, modulates Apoptosis. This small molecule/inhibitor is primarily used fo 125316-60-1 5MG ₹9380 2022-06-14 Buy
Product number Packaging Price Buy
C5865 5MG ₹20556.68 Buy
C5865 25MG ₹81934.43 Buy
178496 5MG ₹9380 Buy

CD437 Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

An intermediate in the preparation of Adapalene derivatives.

Definition

ChEBI: A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)g mma and induces cell cycle arrest and apoptosis in various cancer cells.

Biological Activity

Synthetic retinoid that is an RAR γ -selective agonist. Displays RAR γ -dependent and -independent effects on differentiation and apoptosis.

CD437 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 111)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Simson Pharma Limited 08048372660Ext 600 Mumbai, India 94 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry

CD437 Spectrum

2-naphthalenecarboxylicacid,6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphen 6-(4-hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic AHPN, 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid O-DesMethyl Adapalene CD 437/AHPN Adapalene IMpurity F Apoptosis Activator VI, CD437/AHPN ADAP-IME 6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid CD437;CD-437;CD 437 CS-2691 O-Desmethyl Adapalene-13C6 Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem AHPN;CD 437;CD-437 Apoptosis Activator VI 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthoic Acid 2-Naphthalenecarboxylic acid, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)- 6-(3-(Adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoic acid inhibit,Retinoid X receptors,CD437,CD-437,CD 437,RAR/RXR,Inhibitor,Autophagy,Retinoic acid receptors CD437/6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid Ro 472077 Ro472077 Ro-472077 125316-60-1 Aromatics Intermediates & Fine Chemicals Pharmaceuticals