ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >Histamine Receptor Antagonists >JNJ7777120

JNJ7777120

JNJ7777120 Structure
CAS No.
459168-41-3
Chemical Name:
JNJ7777120
Synonyms
CS-593;JNJ7777120 USP/EP/BP;JNJ-7777120;JNJ7777120;5-CHLORO-2-(4-METHYLPIPERAZINE-1-CARBONYL)-1H-INDOLE;Piperazine,1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methyl-;(5-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone;Methanone, (5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-;Histamine Receptor,JNJ-7777120,JNJ 7777120,Inhibitor,inhibit;(5-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone JNJ 7777120
CBNumber:
CB7503702
Molecular Formula:
C14H16ClN3O
Molecular Weight:
277.75
MOL File:
459168-41-3.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

JNJ7777120 Properties

Boiling point 477.0±45.0 °C(Predicted)
Density 1.322±0.06 g/cm3(Predicted)
storage temp. room temp
solubility H2O: insoluble
pka 15.20±0.30(Predicted)
form solid
color white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
2 0

JNJ7777120 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) J3770 JNJ7777120 ≥98% (HPLC) 459168-41-3 5MG ₹15252.43 2022-06-14 Buy
Sigma-Aldrich(India) J3770 JNJ7777120 ≥98% (HPLC) 459168-41-3 25MG ₹60684.95 2022-06-14 Buy
Product number Packaging Price Buy
J3770 5MG ₹15252.43 Buy
J3770 25MG ₹60684.95 Buy

JNJ7777120 Chemical Properties,Uses,Production

Uses

JNJ7777120 is a histamine 4 receptor (H4R) antagonist on CCL17 and CCL22 chemokine production by human monocyte-derived Langerhans cells in patients with atopic dermatitis.

Biochem/physiol Actions

JNJ7777120 may exhibit neuroprotective effects against ischemic brain damage. It acts as an anti-inflammatory agent to treat inflammatory diseases. JNJ7777120 is observed to reduce colonic injury, cytokine production, and neutrophil infiltration.

JNJ7777120 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 104)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Xi'an MC Biotech, Co., Ltd. 029-89275612 +8618991951683 China 2255 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24639 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
Piperazine,1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methyl- JNJ-7777120;JNJ7777120 (5-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone Methanone, (5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)- (5-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone JNJ 7777120 CS-593 JNJ7777120 USP/EP/BP Histamine Receptor,JNJ-7777120,JNJ 7777120,Inhibitor,inhibit 5-CHLORO-2-(4-METHYLPIPERAZINE-1-CARBONYL)-1H-INDOLE 459168-41-3 C14H16N3OCl Inhibitors