(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID
- CAS No.
- 141110-17-0
- Chemical Name:
- (+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID
- Synonyms
- (+/-)18-HEPE;LRWYBGFSVUBWMO-UXNZXXPISA-N;Eicosapentaenoic Acid Impurity 11;(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID;(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID;(5Z,8Z,11Z,14Z,16E)-18-Hydroxyicosa-5,8,11,14,16-pentaenoic acid;5,8,11,14,16-Eicosapentaenoic acid, 18-hydroxy-, (5Z,8Z,11Z,14Z,16E)-
- CBNumber:
- CB7759853
- Molecular Formula:
- C20H30O3
- Molecular Weight:
- 318.45
- MOL File:
- 141110-17-0.mol
- Modify Date:
- 2024/7/3 17:43:36
| Boiling point | 488.0±45.0 °C(Predicted) |
|---|---|
| Density | 0.997±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml |
| pka | 4.75±0.10(Predicted) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID Chemical Properties,Uses,Production
Description
(±)18-HEPE is produced by non-enzymatic oxidation of eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908). 18-HEPE levels are increased in the plasma and heart, as well as in the supernatant of cultured peritoneal macrophages isolated from fat-1 transgenic mice that are capable of endogenously producing ω-3 fatty acids from ω-6 fatty acids. It reduces increases in cardiac fibrosis and the expression of Nppa, Col1a1, Tgfb1, Cx3cl1, and Adgre1 induced by transverse aortic constriction in a mouse model of cardiac hypertrophy when administered at doses of 1 and 5 μg.
Uses
18-Hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoic Acid is produced by non-enzymatic oxidation of Eicosapentaenoic Acid (E477800).
(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID Suppliers
Global( 21)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +8618627948422 | China | 3389 | 58 | Inquiry |
| Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
| AXXORA, LLC | +41 (0) 61 926 8989 | Switzerland | 1104 | 80 | Inquiry |
| 3B Scientific Corporation | 847.281.9822 | United States | 6744 | 47 | Inquiry |
| United States Biological | 1-800-520-3011 | United States | 6106 | 58 | Inquiry |
| Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | China | 11289 | 58 | Inquiry |
| amyjetsci | 027-59626688 18771149750 | China | 3004 | 58 | Inquiry |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | China | 1977 | 58 | Inquiry |
141110-17-0((+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID)Related Search:
(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID
(+/-)18-HEPE
LRWYBGFSVUBWMO-UXNZXXPISA-N
(5Z,8Z,11Z,14Z,16E)-18-Hydroxyicosa-5,8,11,14,16-pentaenoic acid
5,8,11,14,16-Eicosapentaenoic acid, 18-hydroxy-, (5Z,8Z,11Z,14Z,16E)-
Eicosapentaenoic Acid Impurity 11
(+/-)-18-HYDROXY-5Z,8Z,11Z,14Z,16E-EICOSAPENTAENOIC ACID
141110-17-0