Ethyl 3-(pyridin-2-ylamino)propanoate
![Ethyl 3-(pyridin-2-ylamino)propanoate Structure](CAS/GIF/103041-38-9.gif)
- CAS No.
- 103041-38-9
- Chemical Name:
- Ethyl 3-(pyridin-2-ylamino)propanoate
- Synonyms
- Dabigatran Impurity 83;3-(Pyridin-2-ylamino)propanoate;Dabigatran Etexilate Impurity 90;N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER;Ethyl 3-(pyridin-2-ylamino)propan;Ethyl 3-(2-PyridylaMino)propanoate;Dabigatran Etexilate Intermdiate 4;N-2-pyridinyl-β-Alanine,ethylester;Ethyl 3-(2-Pyridylamino)propionate;N-2-Pyridinyl-β-Alanine,ethylester
- CBNumber:
- CB81011425
- Molecular Formula:
- C10H14N2O2
- Molecular Weight:
- 194.23
- MOL File:
- 103041-38-9.mol
- Modify Date:
- 2024/7/25 20:04:51
Melting point | 48-50°C |
---|---|
Boiling point | 125°C/0.2mmHg(lit.) |
Density | 1.131±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | DMSO, Methanol |
form | Solid |
pka | 6.26±0.10(Predicted) |
color | White |
InChI | InChI=1S/C10H14N2O2/c1-2-14-10(13)6-8-12-9-5-3-4-7-11-9/h3-5,7H,2,6,8H2,1H3,(H,11,12) |
InChIKey | UITNIDFEANEWPC-UHFFFAOYSA-N |
SMILES | C(OCC)(=O)CCNC1C=CC=CN=1 |
LogP | 1.54 at 22℃ and pH6 |
Ethyl 3-(pyridin-2-ylamino)propanoate price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemicals (India) | E1214 | Ethyl 3-(2-Pyridylamino)propionate min. 96.0 % | 103041-38-9 | 5G | ₹2200 | 2022-05-26 | Buy |
TCI Chemicals (India) | E1214 | Ethyl 3-(2-Pyridylamino)propionate min. 96.0 % | 103041-38-9 | 25G | ₹3900 | 2022-05-26 | Buy |
Ethyl 3-(pyridin-2-ylamino)propanoate Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Ethyl 3-(2-Pyridylamino)propanoate is an intermediate used in the synthesis of Dabigatran etexilate, as thrombin inhibitors. Ethyl Ester form of P993315.
Synthesis
A method for preparing Ethyl 3-(pyridin-2-ylamino)propanoate comprises the following steps: using 2-aminopyridine and ethyl acrylate as raw materials, using anhydrous ethanol as a solvent, using trifluoromethanesulfonic acid as a catalyst, and heating in an oil bath to control the temperature at 120 to 160° C. for a catalytic reaction for 16 to 20 hours under nitrogen protection. The obtained reaction solution is washed with petroleum ether at a temperature of 35 to 40° C. and a pressure of 0.09 to 0.1 MPa, then concentrated under reduced pressure, and then washed with petroleum ether/ethyl acetate and recrystallized to obtain white flaky crystals of Ethyl 3-(pyridin-2-ylamino)propanoate.
Ethyl 3-(pyridin-2-ylamino)propanoate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Terma Medicare India Pvt.,Ltd | +8613916485955 | Rajasthan, India | 145 | 58 | Inquiry |
GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
Neochemsys Laboratories Pvt Ltd | +918498007788 | Hyderabad, India | 93 | 58 | Inquiry |
Urantiis Pharmaceuticals Private Limited | +918790703567 | AndhraPradesh, India | 80 | 58 | Inquiry |
SYNGREEN LIFESCIENCES PVT.LTD | +919849474297 | Telangana, India | 82 | 58 | Inquiry |
Vijayasai Lifesciences | +91 9347036508 | AndhraPradesh, India | 54 | 58 | Inquiry |
3A Chemie Private Limited | +91-91-712-2564285 +91-9766589212 | Maharashtra, India | 57 | 58 | Inquiry |
Vihita Chem Private Limited | +91-9512002673 +91-9512002673 | Gujarat, India | 122 | 58 | Inquiry |
VASISTA LIFE SCIENCES PRIVATE LIMITED | +91-04029554774 +91-9010855544 | Hyderabad, India | 153 | 58 | Inquiry |
VASUDHA PHARMA CHEM LIMITED | +91-91-4044763666 +91-9396659284 | Telangana, India | 102 | 58 | Inquiry |
103041-38-9(Ethyl 3-(pyridin-2-ylamino)propanoate)Related Search:
1of2
chevron_right