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Sorbinil

Sorbinil Structure
CAS No.
68367-52-2
Chemical Name:
Sorbinil
Synonyms
CP-45634;(S)-(+)-Sorbinil;Sorbinil >=98% (HPLC);inhibit,Aldose Reductase,Sorbinil,Inhibitor;(+)-(4S)-6-Fluorospiro[chroman-4,4′-imidazolidine]-2′,5′-dione;(4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione;(4S)-6-Fluorospiro[2H-1-benzopyran-4(3H),4'-imidazolidine]-2',5'-dione;(S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione;(4S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione;(4S)-6'-Fluoro-2',3'-dihydrospiro[imidazolidine-4,4'-[4H][1]benzopyran]-2,5-dione
CBNumber:
CB81117527
Molecular Formula:
C11H9FN2O3
Molecular Weight:
236.2
MOL File:
68367-52-2.mol
MSDS File:
SDS
Modify Date:
2023/9/4 15:51:00
Request For Quotation

Sorbinil Properties

Melting point 241-243°
alpha D25 +54.0° (c = 1 in methanol)
Density 1.52
storage temp. 2-8°C
solubility DMSO: ≥20mg/mL
pka 8.91±0.20(Predicted)
form powder
color white to off-white
optical activity [α]/D +50 to +60°, c = 1 in methanol

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3

Sorbinil price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S7701 Sorbinil ≥98% (HPLC) 68367-52-2 5MG ₹13975.08 2022-06-14 Buy
Sigma-Aldrich(India) S7701 Sorbinil ≥98% (HPLC) 68367-52-2 25MG ₹55218.33 2022-06-14 Buy
Product number Packaging Price Buy
S7701 5MG ₹13975.08 Buy
S7701 25MG ₹55218.33 Buy

Sorbinil Chemical Properties,Uses,Production

Uses

Sorbinil has been used as an aldose reductase inhibitor in diabetic rats as a positive control group.

Definition

ChEBI: An azaspiro compound having a monofluoro-substituted chromane skeleton spiro-linked to an imidazolidinedione ring.

Biochem/physiol Actions

Sorbinil decreases the level of sorbitol in red blood cells and increases the velocity of nerve conduction. It maintains the myo-inositol content in the nerve and prevents the reduction of sodium-potassium ATPase activity. This action is beneficial in providing symptomatic relief in patients with diabetic neuropathy.

Sorbinil Preparation Products And Raw materials

Raw materials

Preparation Products

Sorbinil Suppliers

Global( 22)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 China 5014 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9155 58 Inquiry
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 15162312715 China 2992 58 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
2A PharmaChem USA (630) 737-0988 United States 6148 39 Inquiry
Leancare Ltd. +33 962096793 United Kingdom 6460 42 Inquiry
Glentham Life Sciences +44 (2033) 978-798 United Kingdom 1429 0 Inquiry
Shanghai Synchem Pharma Co., ltd 21-619849051-1 18521059765 China 6457 55 Inquiry
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 58
TargetMol Chemicals Inc. 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
RD International Technology Co., Limited 58
Suzhou Zhixin Biotechnology Co., Ltd. 58
3B Scientific Corporation 47
2A PharmaChem USA 39
Leancare Ltd. 42
Glentham Life Sciences 0
Shanghai Synchem Pharma Co., ltd 55

Sorbinil Spectrum

Sorbinil(68367-52-2)1HNMR

68367-52-2(Sorbinil)Related Search:

(S)-1-(3-Fluorophenyl)ethanamine 2-ETHOXYPHENETHYLAMINE H-PHG-NH2 HCL (R)-1-(3-Fluorophenyl)ethylamine 6-FLUOROCHROMAN
3-(4-fluorophenoxy)propan-1-amine N-(2-METHOXYPHENETHYL)UREA 6-FLUORO-4-CHROMANONE HYDANTOIN 1-(3-FLUOROPHENYL)PROPYLAMINE Sorbinil
FIDARESTAT (S)-(+)-NIRVANOL [3-(4-FLUOROPHENOXY)PROPYL]METHYLAMINE (RS)-N-[1-(3-FLUOROPHENYL)ETHYL]METHYLAMINE 2-(2-METHOXYPHENYL)-ACETAMIDE
3-(3-FLUOROPHENYL)-DL-BETA-ALANINOL 2H-1-Benzopyran-4-amine,3,4-dihydro-,(4S)-(9CI) 6-FLUORO-CHROMAN-4-YLAMINE HYDROCHLORIDE
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Spiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione, 6-fluoro-2,3-dihydro-, (4S)- (4S)-6'-Fluoro-2',3'-dihydrospiro[imidazolidine-4,4'-[4H][1]benzopyran]-2,5-dione (4S)-6-Fluorospiro[2H-1-benzopyran-4(3H),4'-imidazolidine]-2',5'-dione (S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione CP-45634 (4S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione (S)-(+)-Sorbinil (+)-(4S)-6-Fluorospiro[chroman-4,4′-imidazolidine]-2′,5′-dione (4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione Sorbinil >=98% (HPLC) inhibit,Aldose Reductase,Sorbinil,Inhibitor 68367-52-2