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Sorbinil

Sorbinil Structure
CAS No.
68367-52-2
Chemical Name:
Sorbinil
Synonyms
CP-45634;(S)-(+)-Sorbinil;Sorbinil >=98% (HPLC);Sorbinil, 10 mM in DMSO;inhibit,Aldose Reductase,Sorbinil,Inhibitor;(+)-(4S)-6-Fluorospiro[chroman-4,4′-imidazolidine]-2′,5′-dione;(4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione;(4S)-6-Fluorospiro[2H-1-benzopyran-4(3H),4'-imidazolidine]-2',5'-dione;(S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione;(4S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione
CBNumber:
CB81117527
Molecular Formula:
C11H9FN2O3
Molecular Weight:
236.2
MOL File:
68367-52-2.mol
MSDS File:
SDS
Modify Date:
2025/4/17 18:22:24
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Sorbinil Properties

Melting point 241-243°
alpha D25 +54.0° (c = 1 in methanol)
Density 1.52
storage temp. 2-8°C
solubility DMSO: ≥20mg/mL
pka 8.91±0.20(Predicted)
form powder
color white to off-white
optical activity [α]/D +50 to +60°, c = 1 in methanol

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3

Sorbinil price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S7701 Sorbinil ≥98% (HPLC) 68367-52-2 5MG ₹13975.08 2022-06-14 Buy
Sigma-Aldrich(India) S7701 Sorbinil ≥98% (HPLC) 68367-52-2 25MG ₹55218.33 2022-06-14 Buy
Product number Packaging Price Buy
S7701 5MG ₹13975.08 Buy
S7701 25MG ₹55218.33 Buy

Sorbinil Chemical Properties,Uses,Production

Uses

Sorbinil has been used as an aldose reductase inhibitor in diabetic rats as a positive control group.

Definition

ChEBI: An azaspiro compound having a monofluoro-substituted chromane skeleton spiro-linked to an imidazolidinedione ring.

Biochem/physiol Actions

Sorbinil decreases the level of sorbitol in red blood cells and increases the velocity of nerve conduction. It maintains the myo-inositol content in the nerve and prevents the reduction of sodium-potassium ATPase activity. This action is beneficial in providing symptomatic relief in patients with diabetic neuropathy.

Sorbinil Preparation Products And Raw materials

Raw materials

Preparation Products

Sorbinil Suppliers

Global( 28)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49732 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32159 58 Inquiry
Proteintech China 027-87531629 CHINA 6290 58 Inquiry
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 China 47255 58 Inquiry
Merck KGaA 21-20338288 China 292394 58 Inquiry
Absin Bioscience Inc. 021-38015121-8802 CHINA 6208 58 Inquiry
Adooq Bioscience LLC 400-025-6535 China 18215 58 Inquiry
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 15162312715 China 2972 58 Inquiry
3B Scientific Corporation 847.281.9822 United States 6718 47 Inquiry
2A PharmaChem USA (630) 737-0988 United States 6137 39 Inquiry
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 58
TargetMol Chemicals Inc. 58
Proteintech China 58
Sangon Biotech (Shanghai) Co.,Ltd. 58
Merck KGaA 58
Absin Bioscience Inc. 58
Adooq Bioscience LLC 58
Suzhou Zhixin Biotechnology Co., Ltd. 58
3B Scientific Corporation 47
2A PharmaChem USA 39

Sorbinil Spectrum

Sorbinil(68367-52-2)1HNMR

68367-52-2(Sorbinil)Related Search:

(S)-1-(3-Fluorophenyl)ethanamine 2-ETHOXYPHENETHYLAMINE H-PHG-NH2 HCL (R)-1-(3-Fluorophenyl)ethylamine 6-FLUOROCHROMAN
3-(4-fluorophenoxy)propan-1-amine N-(2-METHOXYPHENETHYL)UREA 6-FLUORO-4-CHROMANONE HYDANTOIN 1-(3-FLUOROPHENYL)PROPYLAMINE Sorbinil
FIDARESTAT (S)-(+)-NIRVANOL [3-(4-FLUOROPHENOXY)PROPYL]METHYLAMINE (RS)-N-[1-(3-FLUOROPHENYL)ETHYL]METHYLAMINE 2-(2-METHOXYPHENYL)-ACETAMIDE
3-(3-FLUOROPHENYL)-DL-BETA-ALANINOL 2H-1-Benzopyran-4-amine,3,4-dihydro-,(4S)-(9CI) 6-FLUORO-CHROMAN-4-YLAMINE HYDROCHLORIDE
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Spiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione, 6-fluoro-2,3-dihydro-, (4S)- (4S)-6'-Fluoro-2',3'-dihydrospiro[imidazolidine-4,4'-[4H][1]benzopyran]-2,5-dione (4S)-6-Fluorospiro[2H-1-benzopyran-4(3H),4'-imidazolidine]-2',5'-dione (S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione CP-45634 (4S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione (S)-(+)-Sorbinil (+)-(4S)-6-Fluorospiro[chroman-4,4′-imidazolidine]-2′,5′-dione (4S)-6-fluorospiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione Sorbinil >=98% (HPLC) inhibit,Aldose Reductase,Sorbinil,Inhibitor Sorbinil, 10 mM in DMSO 68367-52-2