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Drofenine

Drofenine Structure
CAS No.
1679-76-1
Chemical Name:
Drofenine
Synonyms
Adiphenine H;Trasentin-6H;Cycloadiphene;AGJBLWCLQCKRJP-UHFFFAOYSA-N;2-(DiethylaMino)ethyl 2-cyclohexyl-2-phenylacetate;α-Cyclohexylbenzeneacetic acid 2-(diethylamino)ethyl ester;Benzeneacetic acid, α-cyclohexyl-, 2-(diethylamino)ethyl ester
CBNumber:
CB81178582
Molecular Formula:
C20H31NO2
Molecular Weight:
317.47
MOL File:
1679-76-1.mol
Modify Date:
2023/5/4 17:34:34
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Drofenine Properties

Boiling point bp0.15 158°
Density 1.0047 g/cm3
pka 9.21±0.25(Predicted)

Drofenine Chemical Properties,Uses,Production

Originator

Trasentine A,Ciba

Manufacturing Process

17.4 parts of diphenylacetic acid 2-(diethylamino)ethyl ester were solved in 200 parts of acetic acid and hydrogenated over platinum catalyst. After the calculated volume of hydrogen was passed, the catalyst was filtered off and the solvent was removed to dryness. Ether, water and a potassium carbonate solution were added to the remaining oil and were thoroughly shaken. The ether layer was washed with water and dried over potassium carbonate. The solvent was removed, the remaining oil was distilled in vacuum to give 2- (diethylamino)ethyl α-phenylcyclohexaneacetate; BP 150°-160°C/0.2 mm Hg.
In practice it is usually used as hydrochloride.

Therapeutic Function

Spasmolytic

Drofenine Preparation Products And Raw materials

Raw materials

Adiphenine hydrochloride Platinum

Preparation Products

Drofenine Suppliers

Global( 6)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shanghai New Union Textra Import & Export Co., Ltd +861-348-227-9455 China 2752 60 Inquiry
2A PharmaChem USA (630) 737-0988 United States 6148 39 Inquiry
Leancare Ltd. +33 962096793 United Kingdom 6460 42 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28091 58 Inquiry
Supplier Advantage
Shanghai New Union Textra Import & Export Co., Ltd 60
2A PharmaChem USA 39
Leancare Ltd. 42
TargetMol Chemicals Inc. 58

1679-76-1(Drofenine)Related Search:

Oxyphenonium bromide CYCLOHEXYLPHENYLACETIC ACID Drofenine butetamate 3-Quinuclidinyl alpha-phenylcyclohexaneglycolate
ETHYL CYCLOHEXYLACETATE DROFENINE HYDROCHLORIDE 3-METHYL-2-PHENYLVALERIC ACID
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Adiphenine H Cycloadiphene Trasentin-6H α-Cyclohexylbenzeneacetic acid 2-(diethylamino)ethyl ester 2-(DiethylaMino)ethyl 2-cyclohexyl-2-phenylacetate AGJBLWCLQCKRJP-UHFFFAOYSA-N Benzeneacetic acid, α-cyclohexyl-, 2-(diethylamino)ethyl ester 1679-76-1