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alpha-Methyl-4-biphenylacetic acid

alpha-Methyl-4-biphenylacetic acid Structure
CAS No.
6341-72-6
Chemical Name:
alpha-Methyl-4-biphenylacetic acid
Synonyms
LY-71130;p-Phenylhydratropic Acid;p-Phenylhydroatropic acid;Flurbiprofen EP impurity A;Flurbiprofen impurity A CRS;Flurbiprofen EP impurity A -E;Flurbiprofen axetil impurity5;α-Methylbiphenyl-4-acetic acid;α-Methyl-4-biphenylacetic acid;2-(4-Biphenylyl)propionic Acid
CBNumber:
CB81401675
Molecular Formula:
C15H14O2
Molecular Weight:
226.27
MOL File:
6341-72-6.mol
MSDS File:
SDS
Modify Date:
2023/5/15 10:43:24

alpha-Methyl-4-biphenylacetic acid Properties

Melting point 168-169 °C
Boiling point 388.3±21.0 °C(Predicted)
Density 1.134±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly, Heated)
pka 4.34±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P264-P270-P301+P310-P405-P501
RIDADR  UN 2811 6.1 / PGIII
HS Code  2916399000

alpha-Methyl-4-biphenylacetic acid price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR2710 Flurbiprofen Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard 6341-72-6 100MG ₹56971.98 2022-06-14 Buy
Product number Packaging Price Buy
PHR2710 100MG ₹56971.98 Buy

alpha-Methyl-4-biphenylacetic acid Chemical Properties,Uses,Production

Uses

A metabolite of Isopropylbiphenyl, a COX-2 selective inhibitor. Also an impurity of Flurbiprofen (F598700).

Synthesis Reference(s)

Synthesis, p. 456, 1982 DOI: 10.1055/s-1982-29832

alpha-Methyl-4-biphenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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alpha-Methyl-4-biphenylacetic acid 2-(Biphenyl-4-yl)propanoic acid LY-71130 p-Phenylhydroatropic acid α-Methyl-4-biphenylacetic acid α-Methylbiphenyl-4-acetic acid Flurbiprofen Related CoMpound A (Biprofen) (2RS)-2-(Biphenyl-4-yl)propanoic acid Flurbiprofen EP impurity A -E Flurbiprofen EP impurity A [1,1'-Biphenyl]-4-acetic acid, α-methyl- Flurbiprofen Impurity 1(EP Impurity A) 2-(4-phenylphenyl)propanoic acid 2-([1,1'-Biphenyl]-4-yl)propanoic acid (R)-2-([1,1'-biphenyl]-4-yl)propanoic acid 2-(4-Biphenylyl)propionic Acid 2-(4-Phenylphenyl)propionic Acid Flurbiprofen ImpurityⅠ:Biprofen(α-Methyl-[1,1'-biphenyl]-4-acetic Acid p-Phenylhydratropic Acid Flurbiprofen impurity A CRS (2RS)-2-(Biphenyl-4-yl)propanoic Ac Flurbiprofen Impurity 1(Flurbiprofen EP Impurity A) [1,1'-Biphenyl]-4-aceticacid, a-methyl- Flurbiprofen EP Impurity A (Biprofen) Flurbiprofen axetil impurity1427 Flurbiprofen axetil impurity5 Flurbiprofen impurity A (F0285202) Flurbiprofen Impurity Ⅰ [2-(4-Biphenylyl)propionic acid Flurbiprofen USP Related Compound A 2 - ([1,1 '- biphenyl] - 4-yl) propionic acid Flurbiprofen EP Impurity A(Flurbiprofen Related Compound A) 2-([1,1'-Biphenyl]-4-yl)propanoic acid Flurbiprofen EP Impurity A (Flurbiprofen USP Related Compound A) 6341-72-6 Aromatics Inhibitors Intermediates & Fine Chemicals Pharmaceuticals