B-NICOTYRINE
- CAS No.
- 487-19-4
- Chemical Name:
- B-NICOTYRINE
- Synonyms
- NICOTYRINE;Pyridine, 3-(1-methyl-1H-pyrrol-2-yl)-;β-Nicotyrine;BETA-NICOTYRINE;3-(1-METHYL-1H-PYRROL-2-YL)PYRIDINE;B-NICOTYRINE;3,2’-nicotyrine;alpha-nicotyrine;BETA-NITROTYRINE;Nicotine EP Impurity B
- CBNumber:
- CB8154891
- Molecular Formula:
- C10H10N2
- Molecular Weight:
- 158.2
- MOL File:
- 487-19-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:02:17
| Melting point | 168-169 °C |
|---|---|
| Boiling point | 78-80°C/0/15mm |
| Density | 1.2410 |
| refractive index | 1.6057 (estimate) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met |
| form | Oil |
| pka | pK1:4.76(+1) (25°C) |
| color | Pale Yellow to Brown to Dark Orange |
| Stability | Light, Air Sensitive |
| EPA Substance Registry System | Pyridine, 3-(1-methyl-1H-pyrrol-2-yl)- (487-19-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H335-H302+H312+H332-H315 | |||||||||
| Precautionary statements | P280-P301+P312-P362+P364 | |||||||||
| HS Code | 2939800000 | |||||||||
| NFPA 704 |
|
B-NICOTYRINE Chemical Properties,Uses,Production
Description
The occurrence of this alkaloid in the cigar type of tobacco has been reported by Wenusch and subsequently confirmed by Spath and Kesztler. It forms a colour_x0002_less oil when pure and yields crystalline salts and derivatives, e.g. the p1atinichloride, m.p. 158°C; picrate, m.p. 170-1 °c and the methiodide, m.p. 2l1-3°e. It may also be prepared from nicotine by oxidation with silver oxide, silver acetate or potassium ferricyanide. With Zn and HCI, the base is reduced to nicotine and 4:5-dihydronicotyrine, b.p. 244-6°C, yielding a dipicrate, m.p. l64°e. In the presence of prepared Pt02, the latter may be further reduced to dihydrometanicotine, the dipicrate of which has m.p. 161-2°C. Nicotyrine may be converted directly into nicotine in one operation by controlled hydrogenation in the presence on Pd-e
Chemical Properties
Clear Light Red-Brown Oil
Uses
Nicotryrine is an alkaloid derived from the dehydrogenation of nicotine and its analog, nornicotine. An alkaloid occurring in cigaret smoke.
References
Cahours, Etard., Bull. Soc. Chim. Fr., 34, 449 (1880)
Pictet, Crepieux., Ber., 28, 1904 (1895)
Pictet, Crepieux., ibid, 33, 2355 (1900)
Wibaut, Oberhoff., Rec. trav. Chim., 47,935 (1928)
Wenusch., Biochem. Zeit., 275,361 (1935)
Spath, Kesztler., Ber., 70,2450 (1937)
Spath, Wibaut, Kesztler., ibid, 71, 100 (1938)
B-NICOTYRINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| sgtlifesciences pvt ltd | +8617013299288 | China | 12382 | 58 | Inquiry |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49999 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |